CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024906
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 FI06027p 
Protein Synonyms/Alias
 Tryptophanyl-tRNA synthetase, isoform A; Tryptophanyl-tRNA synthetase, isoform B 
Gene Name
 Aats-trp 
Gene Synonyms/Alias
 CG9735; Dmel_CG9735 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
115LTLREQGKPFYLYTGacetylation[1]
165DDEKTLWKDLKVEDAacetylation[1]
168KTLWKDLKVEDAIKLacetylation[1]
334QIKNKINKYAFSGGRacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 
Functional Description
  
Sequence Annotation
  
Keyword
 Aminoacyl-tRNA synthetase; ATP-binding; Complete proteome; Ligase; Nucleotide-binding; Protein biosynthesis; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 430 AA 
Protein Sequence
MADTKETVVE GVEALTLNGK PDAEPVETGT DAQAQEGATA PTEDVVDPWN VASSNDAGVD 60
YDKLIKRFGS SKIDEELIAR FEKITGKPAH HFIRRGMFFS HRDLHTILTL REQGKPFYLY 120
TGRGPSSGSL HVGHLVPFIM TKWLQETFDV PLVIQLTDDE KTLWKDLKVE DAIKLGRENA 180
KDIVAIGFDV NKTFIFNNLE FVGKCPAMYQ NIIRIQKCVT FNQVKGIFGF GDSDIIGKIG 240
FPAAQAAPAI SSTFPFIFGN RKVHCLIPCA IDQDPYFRMT RDVAPRLGFP KCALIHSTFF 300
PALQGAKTKM SASDQNSAVY LTDTPKQIKN KINKYAFSGG RVSVEEHRKL GGVPEVDVSY 360
QLLKFFLEDD AKLEEVRVAY SKGEMLTGEI KKLAVETLTP IVEQHQAARK LITDEVLDKY 420
FELRPLKFGS 430 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:InterPro.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0004830; F:tryptophan-tRNA ligase activity; IDA:FlyBase.
 GO:0022008; P:neurogenesis; IMP:FlyBase.
 GO:0006436; P:tryptophanyl-tRNA aminoacylation; IDA:FlyBase. 
Interpro
 IPR001412; aa-tRNA-synth_I_CS.
 IPR002305; aa-tRNA-synth_Ic.
 IPR014729; Rossmann-like_a/b/a_fold.
 IPR002306; Trp-tRNA-ligase. 
Pfam
 PF00579; tRNA-synt_1b 
SMART
  
PROSITE
 PS00178; AA_TRNA_LIGASE_I 
PRINTS
 PR01039; TRNASYNTHTRP.