CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-021136
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Basal cell adhesion molecule 
Protein Synonyms/Alias
 B-CAM cell surface glycoprotein; Lutheran antigen; CD239 
Gene Name
 Bcam 
Gene Synonyms/Alias
 Lu 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
346DEEVQLVKKLKLHVAacetylation[1]
446VQGAPELKPNEIKPKacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
 Laminin alpha-5 receptor. May mediate intracellular signaling (By similarity). 
Sequence Annotation
 DOMAIN 26 136 Ig-like V-type 1.
 DOMAIN 141 251 Ig-like V-type 2.
 DOMAIN 268 343 Ig-like C2-type 1.
 DOMAIN 357 436 Ig-like C2-type 2.
 DOMAIN 443 534 Ig-like C2-type 3.
 MOD_RES 592 592 Phosphoserine (By similarity).
 MOD_RES 594 594 Phosphoserine (By similarity).
 CARBOHYD 315 315 N-linked (GlcNAc...) (Potential).
 CARBOHYD 371 371 N-linked (GlcNAc...) (Potential).
 CARBOHYD 378 378 N-linked (GlcNAc...) (Potential).
 DISULFID 47 119 By similarity.
 DISULFID 166 231 By similarity.
 DISULFID 285 331 By similarity.
 DISULFID 379 419 By similarity.
 DISULFID 468 518 By similarity.  
Keyword
 Cell adhesion; Complete proteome; Disulfide bond; Glycoprotein; Immunoglobulin domain; Membrane; Phosphoprotein; Receptor; Reference proteome; Repeat; Signal; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 624 AA 
Protein Sequence
MEPPDARAGL LWLTLLLSGY SGAQAELHVS VPPRVEVMRG EQIALDCTPR EHPENYVLEW 60
LLVDASGARH RLASVEPQGS EFLGTIHNSR GRRPPYKIDS LGRLVIAEAQ VGDERDYVCV 120
VKAGAAGTSE ATSSVRVFAT PEATEVAPNK GTLSVMEQFA QEIATCSSNN GNPVPRITWY 180
QNGQRLDVPM ELNSKGYMTS RTVREASGLY SLTSTLYLRL HKEDRDASFH CAAHYDLPSG 240
QHGRLDSHTF RLTLHYPTEH VEFWVGSPST TEGWVREGDA VQLLCQGDGS PSPEYSFFRE 300
QGNQEEQLNV NLKGNLTLEG VHRSQSGIYG CRVEDYDADE EVQLVKKLKL HVAYLDPLEL 360
SVPEEFSVFL NSSGTVVNCS ARGLPAPIVR WTKDSVTVAD GPILSLDSVT FDSAGTYTCE 420
ASTPTVPLLS RTQSFQLVVQ GAPELKPNEI KPKSGTSWTE GDEVMLTCSA RGFPEPKLTW 480
SQRGDTTPAE PPFEGRGWMS SSLTLKVTSA LSREGVSCEA SNIHGKNGHV FHFGSVAPQT 540
AQAGVAVMAV AVSVGLLLLV VAAFYCMRRK GRPGCCQRAE KGAPPAREPE LSHSGSERPE 600
HTGLLMGGPS GGGRGGNGGF GDEC 624 
Gene Ontology
 GO:0009986; C:cell surface; IEA:Compara.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005886; C:plasma membrane; IEA:Compara.
 GO:0005055; F:laminin receptor activity; IEA:Compara.
 GO:0007155; P:cell adhesion; NAS:RGD.
 GO:0007160; P:cell-matrix adhesion; IEA:Compara. 
Interpro
 IPR013162; CD80_C2-set.
 IPR007110; Ig-like_dom.
 IPR013783; Ig-like_fold.
 IPR003599; Ig_sub.
 IPR003598; Ig_sub2. 
Pfam
 PF08205; C2-set_2 
SMART
 SM00409; IG
 SM00408; IGc2 
PROSITE
 PS50835; IG_LIKE 
PRINTS