CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-035561
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 2'-5'-oligoadenylate synthase 1A 
Protein Synonyms/Alias
  
Gene Name
 Oas1a 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
43NVLCDFLKERCFRDTacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 298 AA 
Protein Sequence
LPWELRSTPS WKLDKFIEVY LLPNTSFRDD VKSAINVLCD FLKERCFRDT VHPVRVSKVV 60
KGGSSGKGTT LKGKSDADLV VFLNNFTSFE DQLNRRGEFI KEIKKQLYEV QREKHFRVKF 120
EVQSSWWPNP RALSFKLSAP HLQQEVEFDV LPAYDVLELW TLNLYSNPDP KIYTILISEC 180
ISLGKEGEFS TCFTELQRNF LKQRPTKLKS LIRLVKHWYQ LCKEKLGKPL PPQYALELLT 240
VYAWERGNGI TEFNTAQGFR TILELVTKYQ QLRIYWTKYY DFQHPDVSKY LHRQLRKS 298 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0003725; F:double-stranded RNA binding; IEA:InterPro.
 GO:0016779; F:nucleotidyltransferase activity; IEA:InterPro.
 GO:0051607; P:defense response to virus; IEA:InterPro.
 GO:0006955; P:immune response; IEA:InterPro. 
Interpro
 IPR006117; 2-5-oligoadenylate_synth_CS.
 IPR006116; 2-5-oligoadenylate_synth_N.
 IPR018952; 2-5-oligoAdlate_synth_1_dom2/C.
 IPR026774; 2-5A_synthase.
 IPR002934; Nucleotidyltransferase. 
Pfam
 PF01909; NTP_transf_2
 PF10421; OAS1_C 
SMART
  
PROSITE
 PS00832; 25A_SYNTH_1
 PS50152; 25A_SYNTH_3 
PRINTS