CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-032021
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 DNA-directed RNA polymerase I subunit RPA34 
Protein Synonyms/Alias
 cDNA FLJ56102, highly similar to Homo sapiens calpastatin (CAST), transcript variant 8, mRNA 
Gene Name
 CAST 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
580SLKFEDAKLAAAISEubiquitination[1]
619DLDDALDKLSDSLGQacetylation[2]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 754 AA 
Protein Sequence
MAFASWWYKT HVSEKTSESP SKPGEKKGSD EKKAASLGSS QSSRTYAGGT ASATKVSASS 60
GATSKSSSMN PTETKAVKTE PEKKSQSTKL SVVHEKKSQE GKPKEHTEPK SLPKQASDTG 120
SNDAHNKKAV SRSAEQQPSE KSTEPKTKPQ DMISAGGESV AGITAISGKP GDKKKEKKSL 180
TPAVPVESKP DKPSGKSGMD AALDDLIDTL GGPEETEEEN TTYTGPEVSD PMSSTYIEEL 240
GKREVTIPPK YRELLAKKEG ITGPPADSSK PIGPDDAIDA LSSDFTCGSP TAAGKKTEKE 300
ESTEVLKAQS AGTVRSAAPP QEKKRKVEKD TMSDQALEAL SASLGTRQAE PELDLRSIKE 360
VDEAKAKEEK LEKCGEDDET IPSEYRLKPA TDKDGKPLLP EPEEKPKPRS ESELIDELSE 420
DFDRSECKEK PSKPTEKTEE SKAAAPAPVS EAVCRTSMCS IQSAPPEPAT LKGTVPDDAV 480
EALADSLGKK EADPEDGKPV MDKVKEKAKE EDREKLGEKE ETIPPDYRLE EVKDKDGKPL 540
LPKESKEQLP PMSEDFLLDA LSEDFSGPQN ASSLKFEDAK LAAAISEVVS QTPASTTQAG 600
APPRDTSQSD KDLDDALDKL SDSLGQRQPD PDENKPMEDK VKEKAKAEHR DKLGERDDTI 660
PPEYRHLLDD NGQDKPVKPP TKKSEDSKKP ADDQDPIDAL SGDLDSCPST TETSQNTAKD 720
KCKKAASSSK APKNGGKAKD SAKTTEETSK PKDD 754 
Gene Ontology
  
Interpro
 IPR026998; Calpastatin.
 IPR001259; Prot_inh_calpain. 
Pfam
 PF00748; Calpain_inhib 
SMART
  
PROSITE
  
PRINTS