CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-043933
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Tetratricopeptide repeat protein 27 
Protein Synonyms/Alias
  
Gene Name
 TTC27 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
11ERAGQHGKAEEILRQubiquitination[1, 2]
44GDHSCYDKAWELSRYubiquitination[2]
60SARAQRSKALLHLRNubiquitination[2]
68ALLHLRNKEFQECVEubiquitination[2, 3]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; Repeat; TPR repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 100 AA 
Protein Sequence
XCYERAGQHG KAEEILRQEL EKKETPSLYC LLGDVLGDHS CYDKAWELSR YRSARAQRSK 60
ALLHLRNKEF QECVECFERS VKINPMQGSG RPEEREKIGE 100 
Gene Ontology
  
Interpro
 IPR001440; TPR-1.
 IPR013026; TPR-contain_dom.
 IPR011990; TPR-like_helical.
 IPR019734; TPR_repeat. 
Pfam
 PF00515; TPR_1 
SMART
  
PROSITE
 PS50005; TPR
 PS50293; TPR_REGION 
PRINTS