CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-004070
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 60S ribosomal protein L7a 
Protein Synonyms/Alias
 Surfeit locus protein 3 
Gene Name
 Rpl7a 
Gene Synonyms/Alias
 Surf-3; Surf3 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
34VVNPLFEKRPKNFGIubiquitination[1]
37PLFEKRPKNFGIGQDubiquitination[1]
48IGQDIQPKRDLTRFVubiquitination[1]
75AILYKRLKVPPAINQubiquitination[2]
97QTATQLLKLAHKYRPubiquitination[1]
131GKGDVPTKRPPVLRAubiquitination[1]
150VTTLVENKKAQLVVIubiquitination[1]
176FLPALCRKMGVPYCIubiquitination[1]
212TQVNSEDKGALAKLVubiquitination[1]
217EDKGALAKLVEAIRTubiquitination[1]
245GGNVLGPKSVARIAKubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level.
 Danielsen JM, Sylvestersen KB, Bekker-Jensen S, Szklarczyk D, Poulsen JW, Horn H, Jensen LJ, Mailand N, Nielsen ML.
 Mol Cell Proteomics. 2011 Mar;10(3):M110.003590. [PMID: 21139048] 
Functional Description
  
Sequence Annotation
 MOD_RES 34 34 N6-acetyllysine (By similarity).
 MOD_RES 97 97 N6-acetyllysine (By similarity).
 MOD_RES 217 217 N6-acetyllysine (By similarity).  
Keyword
 Acetylation; Complete proteome; Reference proteome; Ribonucleoprotein; Ribosomal protein. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 266 AA 
Protein Sequence
MPKGKKAKGK KVAPAPAVVK KQEAKKVVNP LFEKRPKNFG IGQDIQPKRD LTRFVKWPRY 60
IRLQRQRAIL YKRLKVPPAI NQFTQALDRQ TATQLLKLAH KYRPETKQEK KQRLLARAEK 120
KAAGKGDVPT KRPPVLRAGV NTVTTLVENK KAQLVVIAHD VDPIELVVFL PALCRKMGVP 180
YCIIKGKARL GHLVHRKTCT TVAFTQVNSE DKGALAKLVE AIRTNYNDRY DEIRRHWGGN 240
VLGPKSVARI AKLEKAKAKE LATKLG 266 
Gene Ontology
 GO:0016020; C:membrane; IDA:BHF-UCL.
 GO:0042788; C:polysomal ribosome; IDA:HGNC.
 GO:0042254; P:ribosome biogenesis; IEA:InterPro. 
Interpro
 IPR001921; Ribosomal_L7A/L8.
 IPR004038; Ribosomal_L7Ae/L30e/S12e/Gad45.
 IPR018492; Ribosomal_L7Ae/L8/Nhp2.
 IPR004037; Ribosomal_L7Ae_CS. 
Pfam
 PF01248; Ribosomal_L7Ae 
SMART
  
PROSITE
 PS01082; RIBOSOMAL_L7AE 
PRINTS
 PR00881; L7ARS6FAMILY.
 PR00882; RIBOSOMALL7A.