CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-023661
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 WD repeat-containing protein 37 
Protein Synonyms/Alias
  
Gene Name
 WDR37 
Gene Synonyms/Alias
 KIAA0982 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
49MLEGQDSKLPSSVRSubiquitination[1]
396TVKVWDLKNMRSPIAubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
 REPEAT 154 194 WD 1.
 REPEAT 197 236 WD 2.
 REPEAT 279 318 WD 3.
 REPEAT 321 360 WD 4.
 REPEAT 365 403 WD 5.
 REPEAT 406 445 WD 6.
 REPEAT 452 493 WD 7.  
Keyword
 Complete proteome; Polymorphism; Reference proteome; Repeat; WD repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 494 AA 
Protein Sequence
MPTESASCST ARQTKQKRKS HSLSIRRTNS SEQERTGLPR DMLEGQDSKL PSSVRSTLLE 60
LFGQIEREFE NLYIENLELR REIDTLNERL AAEGQAIDGA ELSKGQLKTK ASHSTSQLSQ 120
KLKTTYKAST SKIVSSFKTT TSRAACQLVK EYIGHRDGIW DVSVAKTQPV VLGTASADHT 180
ALLWSIETGK CLVKYAGHVG SVNSIKFHPS EQLALTASGD QTAHIWRYAV QLPTPQPVAD 240
TSISGEDEVE CSDKDEPDLD GDVSSDCPTI RVPLTSLKSH QGVVIASDWL VGGKQAVTAS 300
WDRTANLYDV ETSELVHSLT GHDQELTHCC THPTQRLVVT SSRDTTFRLW DFRDPSIHSV 360
NVFQGHTDTV TSAVFTVGDN VVSGSDDRTV KVWDLKNMRS PIATIRTDSA INRINVCVGQ 420
KIIALPHDNR QVRLFDMSGV RLARLPRSSR QGHRRMVCCS AWSEDHPVCN LFTCGFDRQA 480
IGWNINIPAL LQEK 494 
Gene Ontology
  
Interpro
 IPR020472; G-protein_beta_WD-40_rep.
 IPR015943; WD40/YVTN_repeat-like_dom.
 IPR001680; WD40_repeat.
 IPR019775; WD40_repeat_CS.
 IPR017986; WD40_repeat_dom. 
Pfam
 PF00400; WD40 
SMART
 SM00320; WD40 
PROSITE
 PS00678; WD_REPEATS_1
 PS50082; WD_REPEATS_2
 PS50294; WD_REPEATS_REGION 
PRINTS
 PR00320; GPROTEINBRPT.