UniProt Accession

 COQ7_HUMAN; Q99807; B2RDA9; Q9BTT7; Q9H0T5; Q9UEW5; Q9UNR5 

Genbank Protein ID

 AF098948; AL136647; AK024291; AK315470; AC099518; CH471186; BC003185; AF032900; U81276 

Genbank Nucleotide ID

 AAD43648.1; CAB66582.1; BAB14876.1; BAG37856.1; EAW50268.1; AAH03185.1; AAC69451.1; AAC51120.1 

Protein Name

 Ubiquinone biosynthesis protein COQ7 homolog 

Protein Synonyms/Alias

 Coenzyme Q biosynthesis protein 7 homolog; Timing protein clk-1 homolog 

Gene Name

 COQ7 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
85	SVGPVIQKMWDQEKD	ubiquitination	[1]

Reference

 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473] 

Functional Description

 Involved in lifespan determination in ubiquinone- independent manner. Involved in ubiquinone biosynthesis. Potential central metabolic regulator (By similarity). 

Sequence Annotation

 REPEAT 48 129 1.
 REPEAT 130 217 2.
 REGION 48 217 2 X approximate tandem repeats.
 METAL 60 60 Iron 1 (By similarity).
 METAL 90 90 Iron 1 (By similarity).
 METAL 90 90 Iron 2 (By similarity).
 METAL 93 93 Iron 1 (By similarity).
 METAL 142 142 Iron 2 (By similarity).
 METAL 178 178 Iron 1 (By similarity).
 METAL 178 178 Iron 2 (By similarity).
 METAL 181 181 Iron 2 (By similarity).  

Keyword

 Alternative splicing; Complete proteome; Iron; Membrane; Metal-binding; Mitochondrion; Mitochondrion inner membrane; Polymorphism; Reference proteome; Repeat; Transit peptide; Ubiquinone biosynthesis. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 217 AA 

Protein Sequence

Gene Ontology

 GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
 GO:0005634; C:nucleus; IDA:LIFEdb.
 GO:0016491; F:oxidoreductase activity; IEA:InterPro.
 GO:0046914; F:transition metal ion binding; IEA:InterPro.
 GO:0001306; P:age-dependent response to oxidative stress; IEA:Compara.
 GO:0034599; P:cellular response to oxidative stress; IEA:Compara.
 GO:0008340; P:determination of adult lifespan; IEA:Compara.
 GO:0001701; P:in utero embryonic development; IEA:Compara.
 GO:0042775; P:mitochondrial ATP synthesis coupled electron transport; IEA:Compara.
 GO:0070584; P:mitochondrion morphogenesis; IEA:Compara.
 GO:0001841; P:neural tube formation; IEA:Compara.
 GO:0022008; P:neurogenesis; IEA:Compara.
 GO:0006744; P:ubiquinone biosynthetic process; TAS:Reactome. 

Interpro

 IPR009078; Ferritin-like_SF.
 IPR012347; Ferritin-rel.
 IPR011566; Ubq_synth_Coq7. 

Pfam

 PF03232; COQ7 

SMART

  

PROSITE

  

PRINTS