| Tag | Content |
|---|
| CPLM ID | CPLM-013732 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Glutamine--fructose-6-phosphate aminotransferase [isomerizing] |
Protein Synonyms/Alias | D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine--D-fructose-6-phosphate amidotransferase |
Gene Name | glmS |
Gene Synonyms/Alias | GK0155 |
Created Date | July 27, 2013 |
Organism | Geobacillus kaustophilus (strain HTA426) |
NCBI Taxa ID | 235909 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 109 | IENYEMVKRDYLADV | acetylation | [1] | | 232 | NGETVKRKPFTAELD | acetylation | [1] | | 269 | VIRRIIQKYQDDNGE | acetylation | [1] | | 420 | AAAAAKAKGFELDFD | acetylation | [1] | | 483 | LEGALKLKEISYIQA | acetylation | [1] |
|
Reference | [1] Proteomic analysis of acetylation in thermophilic Geobacillus kaustophilus. Lee DW, Kim D, Lee YJ, Kim JA, Choi JY, Kang S, Pan JG. Proteomics. 2013 Aug;13(15):2278-82. [ PMID: 23696451] |
Functional Description | Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity). |
Sequence Annotation | DOMAIN 2 217 Glutamine amidotransferase type-2.
DOMAIN 283 422 SIS 1.
DOMAIN 452 590 SIS 2.
ACT_SITE 2 2 Nucleophile; for GATase activity (By
ACT_SITE 595 595 For Fru-6P isomerization activity (By |
Keyword | Aminotransferase; Complete proteome; Cytoplasm; Glutamine amidotransferase; Repeat; Transferase. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 600 AA |
Protein Sequence | MCGIVGYIGY QDVKEILLRG LEKLEYRGYD SAGIAVLNES GVHVFKEKGR IADLRRIVDP 60
NVNATVGIGH TRWATHGAPS RVNAHPHQSA SGRFTLVHNG VIENYEMVKR DYLADVAFQS 120
DTDTEVIVQL VEKFVRDGLT TEEAFRKTLS LLKGSYAIAM IDAQDENTIY AAKNKSPLLV 180
GLGDGFNVVA SDAMAMLQVT NQFVELMDGE LVIVTSENVT IQTLNGETVK RKPFTAELDA 240
SDIEKGTYPH YMLKEIDEQP FVIRRIIQKY QDDNGELAID KAIINEVLNA DRLYIVACGT 300
SYHAGLVGKQ LIESWAKIPV EVHIASEFSY NMPLLSEKPL FIFISQSGET ADSRAVLVQT 360
NKLGYKAITI TNVPGSTLSR EADYTLLLHA GPEIAVASTK AYTAQIAVLA ILAAAAAKAK 420
GFELDFDLTK ELAIVANVME MLCDAKEEME KIASDYLTLT RNCFFIGRAV DYYVCLEGAL 480
KLKEISYIQA EGFAGGELKH GTIALIEDGT PVIALATQEH VNLSIRGNVK EVVARGANPC 540
VISMRGLEGD GDRFIIPAVH PDLTPLVSVV PLQLIAYYAA LHRGCDVDKP RNLAKSVTVE 600 |
Gene Ontology | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0030246; F:carbohydrate binding; IEA:InterPro. GO:0004360; F:glutamine-fructose-6-phosphate transaminase (isomerizing) activity; IEA:HAMAP. GO:0016051; P:carbohydrate biosynthetic process; IEA:InterPro. GO:0006541; P:glutamine metabolic process; IEA:HAMAP. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |