UniProt Accession

 MA7D1_HUMAN; Q3KQU3; D3DPS4; Q7L8J5; Q8N905; Q8TAK0; Q9HBQ2; Q9NW29; Q9ULN3 

Genbank Protein ID

 AB033013; AK001212; AK095939; CH471059; CH471059; BC027334; BC106053; AF218002; AL136547; CR457254 

Genbank Nucleotide ID

 BAA86501.2; BAA91557.1; BAC04654.1; EAX07381.1; EAX07382.1; AAH27334.1; AAI06054.1; AAG17244.1; CAB66482.2; CAG33535.1 

Protein Name

 MAP7 domain-containing protein 1 

Protein Synonyms/Alias

 Arginine/proline-rich coiled-coil domain-containing protein 1; Proline/arginine-rich coiled-coil domain-containing protein 1 

Gene Name

 MAP7D1 

Gene Synonyms/Alias

 KIAA1187; PARCC1; RPRC1; PP2464 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
268	HVDSIINKRLSKSSA	ubiquitination	[1]
272	IINKRLSKSSATLWN	ubiquitination	[1, 2, 3]
439	ARERSLKKRQSLPAS	ubiquitination	[3]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [3] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789] 

Functional Description

  

Sequence Annotation

 MOD_RES 47 47 Phosphothreonine.
 MOD_RES 51 51 Phosphothreonine.
 MOD_RES 70 70 Phosphoserine.
 MOD_RES 86 86 Phosphoserine.
 MOD_RES 113 113 Phosphoserine.
 MOD_RES 116 116 Phosphoserine.
 MOD_RES 125 125 Phosphoserine.
 MOD_RES 274 274 Phosphoserine (By similarity).
 MOD_RES 399 399 Phosphoserine.
 MOD_RES 442 442 Phosphoserine.
 MOD_RES 446 446 Phosphoserine.
 MOD_RES 452 452 Phosphoserine.
 MOD_RES 460 460 Phosphoserine.
 MOD_RES 544 544 Phosphoserine.
 MOD_RES 548 548 Phosphoserine.
 MOD_RES 552 552 Phosphoserine.
 MOD_RES 742 742 Phosphoserine.
 MOD_RES 813 813 Phosphothreonine.
 MOD_RES 816 816 Phosphothreonine.
 MOD_RES 834 834 Phosphoserine.
 CROSSLNK 439 439 Glycyl lysine isopeptide (Lys-Gly)  

Keyword

 Alternative splicing; Coiled coil; Complete proteome; Cytoplasm; Cytoskeleton; Isopeptide bond; Phosphoprotein; Polymorphism; Reference proteome; Ubl conjugation. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 841 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
 GO:0005819; C:spindle; IEA:UniProtKB-SubCell. 

Interpro

 IPR008604; E-MAP-115. 

Pfam

 PF05672; MAP7 

SMART

  

PROSITE

  

PRINTS