CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-031705
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein phosphatase 1 regulatory subunit 7 
Protein Synonyms/Alias
  
Gene Name
 PPP1R7 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
31LNHYRIGKIEGFEVLubiquitination[1, 2, 3]
39IEGFEVLKKVKTLCLubiquitination[2]
40EGFEVLKKVKTLCLRubiquitination[2]
42FEVLKKVKTLCLRQNubiquitination[2, 4]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [4] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Leucine-rich repeat; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 221 AA 
Protein Sequence
MEEHELPVDM ETINLDRDAE DVDLNHYRIG KIEGFEVLKK VKTLCLRQNL IKCIENLEEL 60
QSLRELDLYD NQIKKIENLE ALTELEILDI SFNLLRNIEG VDKLTRLKKL FLVNNKISKI 120
ENLSNLHQLQ MLELGSNRIR AIENIDTLTN LESLFLGKNK ITKLQNLDAL TNLTVLSMQS 180
NRLTKIEGLQ NLVNLRELYL SHNGIEVIEG LENNVQDSLT Y 221 
Gene Ontology
  
Interpro
 IPR001611; Leu-rich_rpt.
 IPR025875; Leu-rich_rpt_4. 
Pfam
 PF12799; LRR_4 
SMART
  
PROSITE
 PS51450; LRR 
PRINTS