UniProt Accession

 YTH1_YEAST; Q06102; D6W4A5 

Genbank Protein ID

 U32445; AY558061; BK006949 

Genbank Nucleotide ID

 AAB68077.1; AAS56387.1; DAA11521.1 

Protein Name

 mRNA 3'-end-processing protein YTH1 

Protein Synonyms/Alias

 Yeast 30 kDa homolog 1 

Gene Name

 YTH1 

Gene Synonyms/Alias

 YPR107C 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
10	LIHPDTAKYPFKFEP	acetylation	[1]

Reference

 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919] 

Functional Description

 RNA-binding component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB. 

Sequence Annotation

 ZN_FING 28 59 C3H1-type 1.
 ZN_FING 61 88 C3H1-type 2.
 ZN_FING 89 117 C3H1-type 3.
 ZN_FING 118 145 C3H1-type 4.
 ZN_FING 147 170 C3H1-type 5.  

Keyword

 Complete proteome; Metal-binding; mRNA processing; Nucleus; Reference proteome; Repeat; RNA-binding; Zinc; Zinc-finger. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 208 AA 

Protein Sequence

Gene Ontology

 GO:0005829; C:cytosol; IDA:SGD.
 GO:0005847; C:mRNA cleavage and polyadenylation specificity factor complex; IDA:SGD.
 GO:0003723; F:RNA binding; IDA:SGD.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006379; P:mRNA cleavage; IDA:SGD.
 GO:0006378; P:mRNA polyadenylation; IDA:SGD. 

Interpro

 IPR000571; Znf_CCCH. 

Pfam

  

SMART

 SM00356; ZnF_C3H1 

PROSITE

 PS50103; ZF_C3H1
 PS50158; ZF_CCHC 

PRINTS