| Tag | Content |
|---|
| CPLM ID | CPLM-016388 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Monocarboxylate transporter 12 |
Protein Synonyms/Alias | MCT 12; Solute carrier family 16 member 12 |
Gene Name | Slc16a12 |
Gene Synonyms/Alias | Mct12 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 446 | TQVPFPVKDSDPKLQ | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates (By similarity). |
Sequence Annotation | |
Keyword | Cell membrane; Complete proteome; Membrane; Reference proteome; Symport; Transmembrane; Transmembrane helix; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 486 AA |
Protein Sequence | MTKITRVSLA SPPDGGWGWM IVAGCFLVTI CTRAVTRCIS IFFVEFQTYF AQDYSQTAWI 60
HSIVDCMTML CAPLGSVVSN QLSCQAGIML GGLLASTGFI LGSFATSLKH LYLSLGVLTG 120
LGFALCYSPA IAMVGKYFSR RKALAYGIAM SGSGIGTFIL APVVQLLIEQ FSWRGALLIL 180
GGFVLNLCVC GALMRPITLK EDRSVPEKNH NRESQREDCK QASPYSPLTK ECTETRLCCS 240
LQQEYGFLLM SDFVVLAVSV LFMAYGCSPL FVYLVPYALS VGVSHHQAAF LMSILGVIDI 300
VGNITFGWLT DRRCLKNYRY VCYLFAVALD GLCYLCLPML QTFPLLVPFS CTFGYFDGAY 360
VTLIPVVTAE IVGTTSLSSA LGVVYFLHAV PYLVSPPIAG WLVDTTGSYT AAFLLCGFAM 420
IFSSILLGFV RIVKRMKRTQ VPFPVKDSDP KLQLWTNGSV AYSVARELDQ KDEEPLPKAR 480
SGCNLT 486 |
Gene Ontology | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. GO:0015293; F:symporter activity; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |