CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-043509
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Core-binding factor subunit beta 
Protein Synonyms/Alias
  
Gene Name
 CBFB 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
11VVPDQRSKFENEEFFacetylation[1]
11VVPDQRSKFENEEFFubiquitination[1, 2]
28LSRECEIKYTGFRDRacetylation[1]
28LSRECEIKYTGFRDRubiquitination[1, 2, 3, 4]
Reference
 [1] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Proteome-wide identification of ubiquitylation sites by conjugation of engineered lysine-less ubiquitin.
 Oshikawa K, Matsumoto M, Oyamada K, Nakayama KI.
 J Proteome Res. 2012 Feb 3;11(2):796-807. [PMID: 22053931]
 [4] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 93 AA 
Protein Sequence
MPRVVPDQRS KFENEEFFRK LSRECEIKYT GFRDRPHEER QARFQNACRD GRSEIVYLKA 60
PMILNGVCVI WKGWIDLQRL DGMGCLEFDE ERA 93 
Gene Ontology
 GO:0005634; C:nucleus; IEA:InterPro.
 GO:0003713; F:transcription coactivator activity; IEA:InterPro. 
Interpro
 IPR003417; CBF_beta. 
Pfam
 PF02312; CBF_beta 
SMART
  
PROSITE
  
PRINTS