CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038941
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Suclg2 
Protein Synonyms/Alias
  
Gene Name
 Suclg2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
68FFVASTAKEAQEAAKacetylation[1]
75KEAQEAAKRLNAKEIacetylation[1]
80AAKRLNAKEIVLKAQacetylation[1]
110KGGTKDPKVVGQLAQacetylation[1]
199IDIFEGIKDSQAQRMacetylation[1]
217LGFLGSLKNQAADQIacetylation[1]
225NQAADQIKKLYHLFLacetylation[1]
226QAADQIKKLYHLFLKacetylation[1]
270DNAEFRQKDIFAMDDacetylation[1]
278DIFAMDDKSENEPIEacetylation[1]
337LDLGGGVKESQVYQAacetylation[1]
422VDLEDAAKKAVASVAacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Ligase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 431 AA 
Protein Sequence
MASAVAIAAQ AGKLLRERSL RPRLLAVRSQ AGHLTPRRWL NLQEYQSKKL MSEHGVRVQR 60
FFVASTAKEA QEAAKRLNAK EIVLKAQILA GGRGKGVFDS GLKGGTKDPK VVGQLAQQMI 120
GYNLATKQTP KEGVKVNKVM VAEALDISRE TYLAILMDRS HNGPVLVGSP QGGVDIEEVA 180
ASSPELIFKE QIDIFEGIKD SQAQRMAENL GFLGSLKNQA ADQIKKLYHL FLKIDATQVE 240
VNPFGETPEG QVVCFDAKIN FDDNAEFRQK DIFAMDDKSE NEPIENEAAR YDLKYIGLDG 300
NIACFVNGAG LAMATCDIIF LNGGKPANFL DLGGGVKESQ VYQAFKLLTS DPKVEAILVN 360
IFGGIVNCAI IANGITKACQ ELELKVPLVV RLEGTNVQEA QNILKSSGLP ITSAVDLEDA 420
AKKAVASVAK K 431 
Gene Ontology
 GO:0045244; C:succinate-CoA ligase complex (GDP-forming); IDA:RGD.
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0019003; F:GDP binding; IDA:RGD.
 GO:0046872; F:metal ion binding; IEA:InterPro.
 GO:0046982; F:protein heterodimerization activity; IDA:RGD.
 GO:0004776; F:succinate-CoA ligase (GDP-forming) activity; IDA:RGD.
 GO:0006105; P:succinate metabolic process; IDA:RGD.
 GO:0006104; P:succinyl-CoA metabolic process; IDA:RGD.
 GO:0006099; P:tricarboxylic acid cycle; IDA:RGD. 
Interpro
 IPR011761; ATP-grasp.
 IPR013650; ATP-grasp_succ-CoA_synth-type.
 IPR013815; ATP_grasp_subdomain_1.
 IPR013816; ATP_grasp_subdomain_2.
 IPR005811; CoA_ligase.
 IPR017866; Succ-CoA_synthase_bsu_CS.
 IPR005809; Succ_CoA_synthase_bsu.
 IPR016102; Succinyl-CoA_synth-like. 
Pfam
 PF08442; ATP-grasp_2
 PF00549; Ligase_CoA 
SMART
  
PROSITE
 PS50975; ATP_GRASP
 PS01217; SUCCINYL_COA_LIG_3 
PRINTS