UniProt Accession

 RAN_CHICK; P42558 

Genbank Protein ID

 X66906 

Genbank Nucleotide ID

 CAA47355.1 

Protein Name

 GTP-binding nuclear protein Ran 

Protein Synonyms/Alias

 GTPase Ran; Ras-like protein TC4; Ras-related nuclear protein 

Gene Name

 RAN 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Gallus gallus (Chicken) 

NCBI Taxa ID

 9031 

Lysine Modification

Position	Peptide	Type	References
23	VGDGGTGKTTFVKRH	ubiquitination	[1]
38	LTGEFEKKYVATLGV	ubiquitination	[1]
60	HTNRGPIKFNVWDTA	ubiquitination	[1]
71	WDTAGQEKFGGLRDG	ubiquitination	[1]
99	VTSRVTYKNVPNWHR	ubiquitination	[1]
134	KDRKVKAKSIVFHRK	ubiquitination	[1]
142	SIVFHRKKNLQYYDI	ubiquitination	[1]
152	QYYDISAKSNYNFEK	ubiquitination	[1]
159	KSNYNFEKPFLWLAR	ubiquitination	[1]

Reference

 [1] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789] 

Functional Description

 GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle (By similarity). 

Sequence Annotation

 NP_BIND 17 24 GTP (By similarity).
 NP_BIND 65 69 GTP (By similarity).
 NP_BIND 122 125 GTP (By similarity).  

Keyword

 Complete proteome; GTP-binding; Nucleotide-binding; Nucleus; Protein transport; Reference proteome; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 216 AA 

Protein Sequence

Gene Ontology

 GO:0000785; C:chromatin; IEA:Compara.
 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
 GO:0003924; F:GTPase activity; IEA:InterPro.
 GO:0006886; P:intracellular protein transport; IEA:InterPro.
 GO:0006913; P:nucleocytoplasmic transport; IEA:InterPro.
 GO:0032092; P:positive regulation of protein binding; IEA:Compara.
 GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. 

Interpro

 IPR027417; P-loop_NTPase.
 IPR002041; Ran_GTPase.
 IPR005225; Small_GTP-bd_dom.
 IPR001806; Small_GTPase. 

Pfam

 PF00071; Ras 

SMART

 SM00176; RAN 

PROSITE

 PS51418; RAN 

PRINTS

 PR00627; GTPRANTC4.