CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-044342
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein transport protein Sec16A 
Protein Synonyms/Alias
  
Gene Name
 SEC16A 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
622KSHLVGVKPFEADRAacetylation[1]
1313AFGDRPEKRDNNWRYubiquitination[1, 2]
1773NHSLPFLKFATNEAIubiquitination[2]
1863RLFDPQLKEKPEEESubiquitination[2]
1865FDPQLKEKPEEESLAubiquitination[2]
Reference
 [1] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 2357 AA 
Protein Sequence
MQPPPQTVPS GMAGPPPAGN PRSVFWASSP YRRRANNNAA VAPTTCPLQP VTDPFAFSRQ 60
ALQSTPLGSS SKSSPPVLQG PAPAGFSQHP GLLVPHTHAR DSSQGPCEPL PGPLTQPRAH 120
ASPFSGALTP SAPPGPEMNR SAEVGPSSEP EVQTLPYLPH YIPGVDPETS HGGHPHGNMP 180
GLDRPLSRQN PHDGVVTPAA SPSLPQPGLQ MPGQWGPVQG GPQPSGQHRS PCPEGPVPSG 240
VPCATSVPHF PTPSILHQGP GHEQHSPLVA PPAALPSDGR DEVSHLQSGS HLANNSDPES 300
TFRQNPRIVN HWASPELRQN PGVKNEHRPA SALVNPLARG DSPENRTHHP LGAGAGSGCA 360
PLEADSGASG ALAMFFQGGE TENEENLSSE KAGLSGQADF DDFCSSPGLG RPPAPTHVGA 420
GSLCQALLPG PSNEAAGDVW GDTASTGVPD ASGSQYENVE NLEFVQNQEV LPSEPLNLDP 480
SSPSDQFRYG PLPGPAVPRH GAVCHTGAPD ATLHTVHPDS VSSSYSSRSH GRLSGSARPQ 540
ELVGTFIQQE VGKPEDEASG SFFKQIDSSP VGGETDETTV SQNYRGSVSQ PSTPSPPKPT 600
GIFQTSANSS FEPVKSHLVG VKPFEADRAN VVGEVRETCV RQKQCRPAAA LPDASPGNLE 660
QPPDNMETLC APQVCPLPLN STTEAVHMLP HAGAPPLDTV YPAPEKRPSA RTQGPVKCES 720
PATTLWAQSE LPDFGGNVLL APAAPALYVC AKPQPPVVQP PEEAMSGQQS RNPSSAAPVQ 780
SRGGIGASEN LENPPKMGEE EALQSQASSG YASLLSSPPT ESLQNPPVLI AQPDHSYNLA 840
QPINFSVSLS NSHEKNQSWR EALVGDRPAV SSWALGGDSG ENTSLSGIPT SSVLSLSLPS 900
SVAQSNFPQG SGASEMVSNQ PANLLVQPPS QPVPENLVPE SQKDRKAGSA LPGFANSPAG 960
STSVVLVPPA HGTLVPDGNK ANHSSHQEDT YGALDFTLSR TLENPVNVYN PSHSDSLASQ 1020
QSVASHPRQS GPGAPNLDRF YQQVTKDAQG QPGLERAQQE LVPPQQQASP PQLPKAMFSE 1080
LSNPESLPAQ GQAQNSAQSP ASLVLVDAGQ QLPPRPPQSS SVSLVSSGSG QAAVPSEQPW 1140
PQPVPALAPG PPPQDLAAYY YYRPLYDAYQ PQYSLPYPPE PGAASLYYQD VYSLYEPRYR 1200
PYDGAASAYA QNYRYPEPER PSSRASHSSE RPPPRQGYPE GYYSSKSGWS SQSDYYASYY 1260
SSQYDYGDPG HWDRYHYSAR VRDPRTYDRR YWCDAEYDAY RREHSAFGDR PEKRDNNWRY 1320
DPRFTGSFDD DPDPHRDPYG EEVDRRSVHS EHSARSLHSA HSLASRRSSL SSHSHQSQIY 1380
RSHNVAAGSY EAPLPPGSFH GDFAYGTYRS NFSSGPGFPE YGYPADTVWP AMEQVSSRPT 1440
SPEKFSVPHV CARFGPGGQL IKVIPNLPSE GQPALVEVHS MEALLQHTSE QEEMRAFPGP 1500
LAKDDTHKVD VINFAQNKAM KCLQNENLID KESASLLWNF IVLLCRQNGT VVGTDIAELL 1560
LRDHRTVWLP GKSPNEANLI DFTNEAVEQV EEEESGEAQL SFLTGGPAAA ASSLERETER 1620
FRELLLYGRK KDALESAMKN GLWGHALLLA SKMDSRTHAR VMTRFANSLP INDPLQTVYQ 1680
LMSGRMPAAS TCCGDEKWGD WRPHLAMVLS NLNNNMDVES RTMATMGDTL ASRGLLDAAH 1740
FCYLMAQAGF GVYTKKTTKL VLIGSNHSLP FLKFATNEAI QRTEAYEYAQ SLGAETCPLP 1800
SFQVFKFIYS CRLAEMGLAT QAFHYCEAIA KSILTQPHLY SPVLISQLVQ MASQLRLFDP 1860
QLKEKPEEES LAAPTWLVHL QQVERQIKEG AGVWHQDGAL PQQCPGTPSS EMEQLDRPGL 1920
SQPGALGIAN PLLAVPAPSP EHSSPSVRLL PSAPQTLPDG PLASPARVPM FPVPLPPGPL 1980
EPGPGCVTPG PALGFLEPSG PGLPPGVPPL QERRHLLQEA RSPDPGIVPQ EAPVGNSLSE 2040
LSEENFDGKF ANLTPSRTVP DSEAPPGWDR ADSGPTQPPL SLSPAPETKR PGQAAKKETK 2100
EPKKGESWFF RWLPGKKKTE AYLPDDKNKS IVWDEKKNQW VNLNEPEEEK KAPPPPPTSM 2160
PKTVQAAPPA LPGPPGAPVN MYSRRAAGTR ARYVDVLNPS GTQRSEPALA PADFVAPLAP 2220
LPIPSNLFVP TPDAEEPQLP DGTGREGPAA ARGLANPEPA PEPKVLSSAA SLPGSELPSS 2280
RPEGSQGGEL SRCSSMSSLS REVSQHFNQA PGDLPAAGGP PSGAMPFYNP AQLAQACATS 2340
GSSRLGRIGQ RKHLVLN 2357 
Gene Ontology
 GO:0048208; P:COPII vesicle coating; IEA:InterPro. 
Interpro
 IPR024880; Sec16.
 IPR024340; Sec16_CCD. 
Pfam
 PF12932; Sec16 
SMART
  
PROSITE
  
PRINTS