CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-005009
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 B-cell differentiation antigen CD72 
Protein Synonyms/Alias
 Lyb-2; CD72 
Gene Name
 CD72 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
196QADRQKTKETLQSEEmethylation[1]
Reference
 [1] Large-scale global identification of protein lysine methylation in vivo.
 Cao XJ, Arnaudo AM, Garcia BA.
 Epigenetics. 2013 May 1;8(5):477-85. [PMID: 23644510
Functional Description
 Plays a role in B-cell proliferation and differentiation. 
Sequence Annotation
 DOMAIN 232 352 C-type lectin.
 MOD_RES 7 7 Phosphotyrosine; by LYN (By similarity).
 MOD_RES 39 39 Phosphotyrosine; by LYN (By similarity).
 CARBOHYD 136 136 N-linked (GlcNAc...) (Potential).
 DISULFID 233 244 By similarity.
 DISULFID 261 350 By similarity.
 DISULFID 325 342 By similarity.  
Keyword
 Complete proteome; Disulfide bond; Glycoprotein; Lectin; Membrane; Phosphoprotein; Polymorphism; Reference proteome; Signal-anchor; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 359 AA 
Protein Sequence
MAEAITYADL RFVKAPLKKS ISSRLGQDPG ADDDGEITYE NVQVPAVLGV PSSLASSVLG 60
DKAAVKSEQP TASWRAVTSP AVGRILPCRT TCLRYLLLGL LLTCLLLGVT AICLGVRYLQ 120
VSQQLQQTNR VLEVTNSSLR QQLRLKITQL GQSAEDLQGS RRELAQSQEA LQVEQRAHQA 180
AEGQLQACQA DRQKTKETLQ SEEQQRRALE QKLSNMENRL KPFFTCGSAD TCCPSGWIMH 240
QKSCFYISLT SKNWQESQKQ CETLSSKLAT FSEIYPQSHS YYFLNSLLPN GGSGNSYWTG 300
LSSNKDWKLT DDTQRTRTYA QSSKCNKVHK TWSWWTLESE SCRSSLPYIC EMTAFRFPD 359 
Gene Ontology
 GO:0005887; C:integral to plasma membrane; IDA:UniProtKB.
 GO:0030246; F:carbohydrate binding; IEA:InterPro.
 GO:0005102; F:receptor binding; TAS:ProtInc.
 GO:0004888; F:transmembrane signaling receptor activity; NAS:UniProtKB.
 GO:0007411; P:axon guidance; TAS:Reactome.
 GO:0007155; P:cell adhesion; TAS:ProtInc. 
Interpro
 IPR001304; C-type_lectin.
 IPR016186; C-type_lectin-like.
 IPR016187; C-type_lectin_fold. 
Pfam
 PF00059; Lectin_C 
SMART
 SM00034; CLECT 
PROSITE
 PS00615; C_TYPE_LECTIN_1
 PS50041; C_TYPE_LECTIN_2 
PRINTS