UniProt Accession

 PLIN3_MOUSE; Q9DBG5; Q3TK05; Q8BKV9; Q9CZK1 

Genbank Protein ID

 AK004970; AK012517; AK049537; AK050140; AK132313; AK167214; BC011116 

Genbank Nucleotide ID

 BAB23708.1; BAB28291.1; BAC33798.1; BAC34089.1; BAE21098.1; BAE39340.1; AAH11116.1 

Protein Name

 Perilipin-3 

Protein Synonyms/Alias

 Cargo selection protein TIP47; Mannose-6-phosphate receptor-binding protein 1 

Gene Name

 Plin3 

Gene Synonyms/Alias

 M6prbp1; Tip47 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
65	TVCDVAEKGVKTLTT	acetylation	[1, 2]
116	ILQQPTEKVLADTKE	ubiquitination	[3]
322	DAEKDPAKPEQVEAR	ubiquitination	[3]

Reference

 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [2] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337]
 [3] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 Required for the transport of mannose 6-phosphate receptors (MPR) from endosomes to the trans-Golgi network (By similarity). 

Sequence Annotation

 MOD_RES 2 2 N-acetylserine (By similarity).
 MOD_RES 65 65 N6-acetyllysine (By similarity).
 MOD_RES 130 130 Phosphoserine (By similarity).
 MOD_RES 174 174 Phosphothreonine (By similarity).
 MOD_RES 179 179 Phosphoserine (By similarity).
 MOD_RES 183 183 Phosphoserine (By similarity).  

Keyword

 3D-structure; Acetylation; Coiled coil; Complete proteome; Cytoplasm; Endosome; Lipid droplet; Membrane; Phosphoprotein; Reference proteome; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 437 AA 

Protein Sequence

Gene Ontology

 GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
 GO:0005811; C:lipid particle; IEA:UniProtKB-SubCell.
 GO:0006810; P:transport; IEA:UniProtKB-KW. 

Interpro

 IPR004279; Perilipin. 

Pfam

 PF03036; Perilipin 

SMART

  

PROSITE

  

PRINTS