| Tag | Content |
|---|
| CPLM ID | CPLM-008765 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Protein transport protein DSL1 |
Protein Synonyms/Alias | Dependent on SLY1-20 protein 1 |
Gene Name | DSL1 |
Gene Synonyms/Alias | YNL258C; N0842 |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 392 | TMSEKIGKNDSDVQN | ubiquitination | [1] |
|
Reference | [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Nat Methods. 2013 Jul;10(7):676-82. [ PMID: 23749301] |
Functional Description | Required for protein transport between the Golgi and the endoplasmic reticulum. May tether coatomer-coated retrograde transport vesicles to the ER membrane through interaction with coatomer as well as the SNARE complex. May contribute to the stabilization of the SNARE complex. |
Sequence Annotation | REGION 1 200 Interaction with TIP20.
REGION 406 459 Interaction with RET2.
REGION 406 440 Interaction with RET1. |
Keyword | 3D-structure; Complete proteome; Endoplasmic reticulum; ER-Golgi transport; Membrane; Protein transport; Reference proteome; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 754 AA |
Protein Sequence | MESLFPNKGE IIRELLKDPL ILKNDSKRSN GSELELDSSD LLQREAILAN ELNILDNLKT 60
FLNLIKEVKT NLNILELENC YYSLQSLRKK MRNNAAYLKQ SFNFQQSIST YVDTLHLELV 120
STLYKILTNG FWKITENSIQ FTPTVEWGKD KVHIEYDTFM DFVAQQYFPK GSLDNQAWFI 180
LDMTSADSQE QVRAKLNTIM KEYMNLSRIV SMIKNSIFIS GKEISYENEK NILVFSKSSS 240
HGQHCVSTVL TSFEAVCDFM LDGLAFRDRK TLSYELGPLF NTEFTKFVKN NASIILESLD 300
SPLKNLVSVI NNKLTRLVAK SEVTNWTHSG KEIQDLLMNK QLYYNLLLDK VLESHISEIR 360
SIFEDPKKSW QNLEVVELTT SNTNTMSEKI GKNDSDVQNE KELHNAVSKD DDWNWEVEDD 420
DADAWGDEID VNIDDEEEKT NQEKEKEPEE EENAWDEAWA IDENIDDASL ENGKEHLKAH 480
DVGSLDKDHI EVTQLPKLFL AISQNFKSSF ADSHVDEQYF AYKYNLLQTS YMAMCTANFS 540
HNWCQLYVDM RYLIERDEKL YRIKELTRNL LETKLNMKYR IVCQLIRHQL TEFRENERNP 600
SWDATIEKLL PYILKEIVRP LQKIRGEEGS RYLLSFLNFL YNDCVTKEIL KWQIISEVNS 660
ENLGELVSLL VNNTDIQLLA KEPSYKKMRE KFATMGKFLP LHLKEIMEMF YNGDFYLFAT 720
DELIQWIELL FADTPLRRNA IDDIYEIRGT ALDD 754 |
Gene Ontology | GO:0070939; C:Dsl1p complex; IDA:SGD. GO:0005783; C:endoplasmic reticulum; IDA:SGD. GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell. GO:0005634; C:nucleus; IDA:SGD. GO:0032581; P:ER-dependent peroxisome organization; IMP:SGD. GO:0015031; P:protein transport; IEA:UniProtKB-KW. GO:0006890; P:retrograde vesicle-mediated transport, Golgi to ER; IMP:SGD. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |