CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-045306
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 GRAM domain-containing protein 1A 
Protein Synonyms/Alias
  
Gene Name
 GRAMD1A 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
138GSDSSSEKGGVPGTPubiquitination[1]
174SMLSPTYKQRNEDFRubiquitination[2]
186DFRKLFSKLPEAERLubiquitination[2, 3]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [3] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 807 AA 
Protein Sequence
MDDVLPLMPW ETLLAQGSPQ GSPDLPAGQR KQQPQGDRAQ GLASESWKLL EVPIIHITPS 60
SDGESPACTP TPRRRQQQRM PDPQSLSQDS TTPHSGRSTP SSSPSLRKRL QLLPPSRPPP 120
EPEPGTMVEK GSDSSSEKGG VPGTPSTQSL GSRNFIRNSK KMQSWYSMLS PTYKQRNEDF 180
RKLFSKLPEA ERLIVDYSCA LQREILLQGR LYLSENWICF YSNIFRWETT ISIQLKEVTC 240
LKKEKTAKLI PNAIQICTES EKHFFTSFGA RDRCFLLIFR LWQNALLEKT LSPRELWHLV 300
HQCYGSELGL TSEDEDYVSP LQLNGLGTPK EVGDVIALSD ITSSGAADRS QEPSPVGSRR 360
GHVTPNLSRA SSDADHGAEE DKEEQVDSQP DASSSQTVTP VAEPPSTEPT QPDGPTTLGP 420
LDLLPSEELL TDTSNSSSST GEEADLAALL PDLSGRLLIN SVFHVGAERL QQMLFSDSPF 480
LQGFLQQCKF TDVTLSPWSG DSKCHQRRVL TYTIPISNPL GPKSASVVET QTLFRRGPQA 540
GGCVVDSEVL TQGIPYQDYF YTAHRYCILG LARNKARLRV SSEIRYRKQP WSLVKSLIEK 600
NSWSGIEDYF HHLERELAKA EKLSLEEGGK DARGLLSGLR RRKRPLSWRA HGDGPQHPDP 660
DPCARAGIHT SGSLSSRFSE PSVDQGPGAG IPSALVLISI VLIILIALNV LLFYRLWSLE 720
RTAHTFESWH SLALAKGKFP QTATEWAEIL ALQKQFHSVE VHKWRQILRA SVELLDEMKF 780
SLEKLHQGIT VSDPPFDTQP RPDDSFS 807 
Gene Ontology
  
Interpro
 IPR004182; GRAM. 
Pfam
 PF02893; GRAM 
SMART
 SM00568; GRAM 
PROSITE
  
PRINTS