UniProt Accession

 SRTD3_HUMAN; Q9UJW9; B3KQB3; Q96CQ2 

Genbank Protein ID

 AF192529; AK074604; CH471126; BC014061; BC050643 

Genbank Nucleotide ID

 AAF05761.1; BAG51975.1; EAW56966.1; AAH14061.1; AAH50643.1 

Protein Name

 SERTA domain-containing protein 3 

Protein Synonyms/Alias

 Replication protein-binding trans-activator; RPA-binding trans-activator 

Gene Name

 SERTAD3 

Gene Synonyms/Alias

 RBT1 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
40	LLRISLDKVQRSLGP	ubiquitination	[1]
161	IDTSAVEKEPARAPP	ubiquitination	[2]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 

Functional Description

 Strong transcriptional coactivator. 

Sequence Annotation

 DOMAIN 26 73 SERTA.  

Keyword

 Activator; Complete proteome; Nucleus; Reference proteome; Transcription; Transcription regulation. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 196 AA 

Protein Sequence

Gene Ontology

 GO:0005634; C:nucleus; IDA:MGI.
 GO:0030308; P:negative regulation of cell growth; IDA:MGI.
 GO:0045893; P:positive regulation of transcription, DNA-dependent; IEA:Compara.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 

Interpro

 IPR009263; SERTA. 

Pfam

 PF06031; SERTA 

SMART

  

PROSITE

 PS51053; SERTA 

PRINTS