CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-043449
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 UPF0420 protein C16orf58 
Protein Synonyms/Alias
  
Gene Name
 C16orf58 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
331LNQKAGPKTILRAATubiquitination[1]
369RVRAGPKKESWVVVKubiquitination[1]
388VLDMLFPKFLKGLQDubiquitination[1, 2, 3]
391MLFPKFLKGLQDAGWubiquitination[1, 2]
399GLQDAGWKTEKHQLEubiquitination[1]
402DAGWKTEKHQLEVDEubiquitination[1, 3, 4]
420TWLLSPEKKVL****ubiquitination[2]
421WLLSPEKKVL*****ubiquitination[1, 2]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [3] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [4] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 423 AA 
Protein Sequence
MADDAGLETP LCSEQFGSGE ARGCRAAADG SLQWEGFPDS VSPDYLPYQL WDSVQAFASS 60
LSGSLATQAV LLGIGVGNAK ATVSAATATW LVKDSTGMLG RIVFAWWKGS KLDCNAKQWR 120
LFADILNDVA MFLEIMAPVY PICFTMTVST SNLAKCIVSV AGGATRAALT VHQARRNNMA 180
DVSAKDSSQE TLVNLAGLLV SLLMLPLVSG CPGFSLGCFF FLTALHIYAN YRAVRALVME 240
TLNEGRLRLV LKHYLQRGEV LDPTAANRME PLWTGFWPAP SLSLGVPLHR LVSSVFELQQ 300
LVEGHQESYL LCWDQSQNQV QVVLNQKAGP KTILRAATHG LMLGALQGDG PLPAELEELR 360
NRVRAGPKKE SWVVVKETHE VLDMLFPKFL KGLQDAGWKT EKHQLEVDEW RATWLLSPEK 420
KVL 423 
Gene Ontology
  
Interpro
 IPR006968; DUF647. 
Pfam
 PF04884; DUF647 
SMART
  
PROSITE
  
PRINTS