CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-031167
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 SUMO-interacting motif-containing protein 1 
Protein Synonyms/Alias
 cDNA FLJ56998 
Gene Name
 SIMC1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
420VMETPARKEISLSEPubiquitination[1, 2]
429ISLSEPAKPGSAHVQubiquitination[1, 2]
482TRENKGQKLEPIPHRubiquitination[1]
562QLHPANAKTVEWDWKubiquitination[3]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [3] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 611 AA 
Protein Sequence
MEDFIVISDD SGSESSGGAR PGRSRRPRRA LSRTSGALPR RTVDFIDLTR ETRPRTKDRS 60
GLYVIDLTRA EGENRPIATL DLTLEPVTPS QKEPTSLQTC ASLSGKAVME GHVDRSSQPT 120
ARRIINSDPV DLDLVEENTF VGPPPATSIS GGSVYPTEPN CSSATFTGNL SFLASLQLSS 180
DVSSLSPTSN NSRSSSSSSN QKAPLPCPQQ DVSRPPQALP CPLRPLPCPP RASPCPPRAS 240
SCPPRALSCP SQTMQCQLPA LTHPPQEVPC PRQNIPGPPQ DSLGLPQDVP GLPQSILHPQ 300
DVAYLQDMPR SPGDVPQSPS DVSPSPDAPQ SPGGMPHLPG DVLHSPGDMP HSSGDVTHSP 360
RDIPHLPGDR PDFTQNDVQN RDMPMDISAL SSPSCSPSPQ SETPLEKVPW LSVMETPARK 420
EISLSEPAKP GSAHVQSRTP QGGLYNRPCL HRLKYFLRPP VHHLFFQTLI PDKDTRENKG 480
QKLEPIPHRR LRMVTNTIEE NFPLGTVQFL MDFVSPQHYP PREIVAHIIQ KILLSGSETV 540
DVLKEAYMLL MKIQQLHPAN AKTVEWDWKL LTYVMEEEPA ECLRLQARAT TPDWFWWRRG 600
FAVLAGPVSS P 611 
Gene Ontology
  
Interpro
  
Pfam
  
SMART
  
PROSITE
  
PRINTS