UniProt Accession

 F5H8L5_HUMAN; F5H8L5 

Genbank Protein ID

 AC096967; AC107310; AC108742 

Genbank Nucleotide ID

  

Protein Name

 Tyrosine-protein kinase RYK 

Protein Synonyms/Alias

  

Gene Name

 RYK 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
164	HGILIDEKDPNKEKQ	ubiquitination	[1]

Reference

 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 418 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0005886; C:plasma membrane; IEA:Compara.
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
 GO:0042813; F:Wnt-activated receptor activity; IEA:Compara.
 GO:0071679; P:commissural neuron axon guidance; IEA:Compara.
 GO:0022038; P:corpus callosum development; IEA:Compara.
 GO:0050919; P:negative chemotaxis; IEA:Compara.
 GO:0048843; P:negative regulation of axon extension involved in axon guidance; IEA:Compara.
 GO:0048705; P:skeletal system morphogenesis; IEA:Compara.
 GO:0016055; P:Wnt receptor signaling pathway; IEA:Compara. 

Interpro

 IPR011009; Kinase-like_dom.
 IPR000719; Prot_kinase_cat_dom.
 IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
 IPR008266; Tyr_kinase_AS.
 IPR020635; Tyr_kinase_cat_dom. 

Pfam

 PF07714; Pkinase_Tyr 

SMART

 SM00219; TyrKc 

PROSITE

 PS50011; PROTEIN_KINASE_DOM
 PS00109; PROTEIN_KINASE_TYR 

PRINTS

 PR00109; TYRKINASE.