CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-037174
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Nuclear receptor corepressor 1 
Protein Synonyms/Alias
  
Gene Name
 NCOR1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
260IFEGLGPKVELPLYNubiquitination[1]
273YNQPSDTKVYHENIKubiquitination[1]
303KKLILFFKRRNHARKubiquitination[2]
Reference
 [1] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Nucleus; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 537 AA 
Protein Sequence
MSSSGYPPNQ GAFSTEQSRY PPHSVQYTFP NTRHQQEFAV PDYRSSHLEV SQASQLLQQQ 60
QQQQLRRRPS LLSEFHPGSD RPQERRTSYE PFHPGPSPVD HDSLESKRPR LEQVSDSHFQ 120
RVSAAVLPLV HPLPEGLRAS ADAKKDPAFG GKHEAPSSPI SGQPCGDDQN ASPSKLSKEE 180
LIQSMDRVDR EIAKVEQQIL KLKKKQQQLE EEAAKPPEPE KPVSPPPVEQ KHRSIVQIIY 240
DENRKKAEEA HKIFEGLGPK VELPLYNQPS DTKVYHENIK TGVPARRMMK NQVMRKKLIL 300
FFKRRNHARK QREQKICQRY DQLMEAWEKK VDRIENNPRR KAKESKTREY YEKQFPEIRK 360
QREQQERFQR VGQRGAGLSA TIARSEHEIS EIIDGLSEQE NNEKQMRQLS VIPPMMFDAE 420
QRRVKFINMN GLMEDPMKVY KDRQFMNVWT DHEKEIFKDK FIQHPKNFGL IASYLERKSV 480
PDCVLYYYLT KKNENYKALV RRNYGKRRGR NQQIARPSQE EKVEEKEEDK AEKTEKK 537 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-KW.
 GO:0003682; F:chromatin binding; IEA:InterPro.
 GO:0003677; F:DNA binding; IEA:InterPro. 
Interpro
 IPR009057; Homeodomain-like.
 IPR001005; SANT/Myb.
 IPR017884; SANT_dom. 
Pfam
 PF00249; Myb_DNA-binding 
SMART
 SM00717; SANT 
PROSITE
 PS51293; SANT 
PRINTS