CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-017247
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 39S ribosomal protein L47, mitochondrial 
Protein Synonyms/Alias
 L47mt; MRP-L47 
Gene Name
 Mrpl47 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
146DSMDNVDKVVQEREDacetylation[1, 2, 3]
184RIVWHKFKQWPIPWYacetylation[4]
184RIVWHKFKQWPIPWYsuccinylation[4]
Reference
 [1] Quantitative assessment of the impact of the gut microbiota on lysine epsilon-acetylation of host proteins using gnotobiotic mice.
 Simon GM, Cheng J, Gordon JI.
 Proc Natl Acad Sci U S A. 2012 Jul 10;109(28):11133-8. [PMID: 22733758]
 [2] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ.
 Mol Cell. 2013 Jan 10;49(1):186-99. [PMID: 23201123]
 [3] Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation.
 Still AJ, Floyd BJ, Hebert AS, Bingman CA, Carson JJ, Gunderson DR, Dolan BK, Grimsrud PA, Dittenhafer-Reed KE, Stapleton DS, Keller MP, Westphall MS, Denu JM, Attie AD, Coon JJ, Pagliarini DJ.
 J Biol Chem. 2013 Jul 17;. [PMID: 23864654]
 [4] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337
Functional Description
  
Sequence Annotation
 MOD_RES 146 146 N6-acetyllysine (By similarity).  
Keyword
 Acetylation; Complete proteome; Mitochondrion; Reference proteome; Ribonucleoprotein; Ribosomal protein; Transit peptide. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 252 AA 
Protein Sequence
MAATSLVGIC RRASAFLKAA CSLVNPKDAA HSGCRSSLSL LHKNTPHVTS FLQCKLLHTT 60
LSRKGLEEFF DDPKNWGEEK VKSGASWTCQ QLRNKSNEDL HKLWYVLLKE RNMLLTLEQE 120
AKRQRLPMPS PERLEKVVDS MDNVDKVVQE REDALRLLQT GQEKPRPGAW RRDIFGRIVW 180
HKFKQWPIPW YLNKRYNRRR FFAMPYVDRF IRLRIEKHAR IEARKRSLQK KKEKILHAKF 240
PHLSQERKSS SV 252 
Gene Ontology
 GO:0005761; C:mitochondrial ribosome; IEA:InterPro.
 GO:0005739; C:mitochondrion; IDA:MGI.
 GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
 GO:0006412; P:translation; IEA:InterPro. 
Interpro
 IPR010729; Ribosomal_L47_mit. 
Pfam
 PF06984; MRP-L47 
SMART
  
PROSITE
  
PRINTS