UniProt Accession

 COQ7_MOUSE; P97478; Q9R0D7 

Genbank Protein ID

 AF080580; AF098949; BC038681; AF053770; U81277; AA030846 

Genbank Nucleotide ID

 AAC31572.1; AAD43649.1; AAH38681.1; AAC69179.1; AAC53055.1 

Protein Name

 Ubiquinone biosynthesis protein COQ7 homolog 

Protein Synonyms/Alias

 Coenzyme Q biosynthesis protein 7 homolog; Timing protein clk-1 homolog 

Gene Name

 Coq7 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
91	QKMWDQEKNHLKKFN	acetylation	[1]
95	DQEKNHLKKFNELMI	acetylation	[1]

Reference

 [1] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ.
 Mol Cell. 2013 Jan 10;49(1):186-99. [PMID: 23201123] 

Functional Description

 Involved in lifespan determination in ubiquinone- independent manner. Involved in ubiquinone biosynthesis. Potential central metabolic regulator. 

Sequence Annotation

 REPEAT 48 129 1.
 REPEAT 130 217 2.
 REGION 48 217 2 X approximate tandem repeats.
 METAL 60 60 Iron 1 (By similarity).
 METAL 90 90 Iron 1 (By similarity).
 METAL 90 90 Iron 2 (By similarity).
 METAL 93 93 Iron 1 (By similarity).
 METAL 142 142 Iron 2 (By similarity).
 METAL 178 178 Iron 1 (By similarity).
 METAL 178 178 Iron 2 (By similarity).
 METAL 181 181 Iron 2 (By similarity).  

Keyword

 Complete proteome; Iron; Membrane; Metal-binding; Mitochondrion; Mitochondrion inner membrane; Reference proteome; Repeat; Transit peptide; Ubiquinone biosynthesis. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 217 AA 

Protein Sequence

Gene Ontology

 GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
 GO:0005739; C:mitochondrion; IDA:MGI.
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0016491; F:oxidoreductase activity; IEA:InterPro.
 GO:0046914; F:transition metal ion binding; IEA:InterPro.
 GO:0001306; P:age-dependent response to oxidative stress; IMP:MGI.
 GO:0034599; P:cellular response to oxidative stress; IMP:MGI.
 GO:0008340; P:determination of adult lifespan; IMP:MGI.
 GO:0001701; P:in utero embryonic development; IMP:MGI.
 GO:0042775; P:mitochondrial ATP synthesis coupled electron transport; IMP:MGI.
 GO:0070584; P:mitochondrion morphogenesis; IMP:MGI.
 GO:0001841; P:neural tube formation; IMP:MGI.
 GO:0022008; P:neurogenesis; IMP:MGI.
 GO:0006744; P:ubiquinone biosynthetic process; IMP:MGI. 

Interpro

 IPR009078; Ferritin-like_SF.
 IPR012347; Ferritin-rel.
 IPR011566; Ubq_synth_Coq7. 

Pfam

 PF03232; COQ7 

SMART

  

PROSITE

  

PRINTS