CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-031853
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Transcriptional adaptor, putative 
Protein Synonyms/Alias
 Transcriptional co-activator ADA2-A 
Gene Name
 TGME49_017050, TGVEG_037130 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Toxoplasma gondii 
NCBI Taxa ID
 5811 
Lysine Modification
Position
Peptide
Type
References
245GEMLGAEKMSAGKSRacetylation[1]
250AEKMSAGKSRRPRETacetylation[1]
671AEMEEAQKERGTQETacetylation[1, 2]
Reference
 [1] Protein intrinsic disorder in the acetylome of intracellular and extracellular Toxoplasma gondii.
 Xue B, Jeffers V, Sullivan WJ, Uversky VN.
 Mol Biosyst. 2013 Apr 5;9(4):645-57. [PMID: 23403842]
 [2] Lysine acetylation is widespread on proteins of diverse function and localization in the protozoan parasite Toxoplasma gondii.
 Jeffers V, Sullivan WJ Jr.
 Eukaryot Cell. 2012 Jun;11(6):735-42. [PMID: 22544907] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Hydrolase; Nucleus; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1203 AA 
Protein Sequence
MESGSSRGGG PGGQGLSTSQ PVSSPGNRSA LPYAASPFVL SSTFPSSHPL PLAPPAYSPS 60
RPPYGTFFAE PAVSPYRPPC ASSDSQTPLL AASSKPTCPP ENEKSSPFLG PPSDSSGGNA 120
TPSIPSSFSS SVPSSLPSSL PSSLPSSLPP PLPSSNAPYP SFYPMHPGAR NVYFPGYGQP 180
WQTTGAPPSG PAAVFPAQRL PPQTPPGLGP AAAAQETGAV HARTPSVLLS GEQTRREGEM 240
LGAEKMSAGK SRRPRETTGN NGPEQGTGQP ERAGPTQGFA FPGSQVYVHP ASRGGPGAAF 300
PQNGGDTQGF AATGAFGSGG GGTFSSQFQQ SGETPQSATG VGRPAPGGVC TPGGGPGYPS 360
PYPGCQGGFP QYVSPPASSS AQISSSSFTC EKKSQAERTE DEERRAKRAK AEPGDGVSPG 420
ACGTPGASQT AAAAELGFAP NREERVSGPV GNEDQRVASL PRNGAPVQTP KTASSSAHAS 480
SARPSSVPAS ASHPSSLSSG LPPLEALPMD QRMGSLVEDL GAFGLAQYHC DVCTKDISTV 540
CRIRCAECED FDLCVACFCM GAEVEGKPHR NSHRYIPIGR NAFPLLRRNW TADEELRLLE 600
GVSKYGFGNW NDVADLVNSV ALTAKTSAEC EQHYTEVYLN SRTSPLPDTS ALLMGRDGGP 660
LKLAEMEEAQ KERGTQETSK TGEEEKKEGE NAEHDEDDAS RPAGGVAPPS RAGTAKPTHS 720
IVGYWPLRGD FDVEYDNDAE LILADMEFKE DEAVQERYLK LQIIEIYNSK LDERLYRKRT 780
VINRGLLDTK TLHQREKKRT KEERDLHNLF KPLARFHSDE EQERLVQLLI EEKRIRARLS 840
MLHEWKSLGL KTADDVGEYE GDKSWREQLQ RFRASELSSL FFSGGLANLF AKHATAQQTG 900
RPLPHAASGA KLCMSPSAAG CAYAAPETPS PGPTGGAGDT PTHSNASSPS AGSGASLSMP 960
VSVVEKGNGE KALEKGKREA KEKADDKGRF FKGGRSSPGD KEDDTLPITA FPGAGLLTEK 1020
ERAFCEDAQL APVFYLLAKR MLLREMAKHK KFNATDFSKP MELYVNRVGQ LYDFYVNVSD 1080
FAPAGVSPNN TVSSRGPALA ISGNAASVVS PRPPVSPPAM GSSVGGAAPV TAAFYRTVAG 1140
ATPGIEPVYN TVNGGVALQP SSGYAHPAVS AKHDAGTGPL CGSPHGRTNQ GDLGLLTEAR 1200
DAC 1203 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-KW.
 GO:0003682; F:chromatin binding; IEA:InterPro.
 GO:0003677; F:DNA binding; IEA:InterPro.
 GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0035335; P:peptidyl-tyrosine dephosphorylation; IEA:GOC. 
Interpro
 IPR009057; Homeodomain-like.
 IPR001005; SANT/Myb.
 IPR017884; SANT_dom.
 IPR000433; Znf_ZZ. 
Pfam
 PF00249; Myb_DNA-binding
 PF00569; ZZ 
SMART
 SM00717; SANT
 SM00291; ZnF_ZZ 
PROSITE
 PS51293; SANT
 PS01357; ZF_ZZ_1
 PS50135; ZF_ZZ_2 
PRINTS