CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-018574
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Uridine-cytidine kinase-like 1 
Protein Synonyms/Alias
  
Gene Name
 Uckl1 
Gene Synonyms/Alias
 Urkl1 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
261KQYNKFVKPAFDQYIubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 May contribute to UTP accumulation needed for blast transformation and proliferation (By similarity). 
Sequence Annotation
 NP_BIND 105 112 ATP (Potential).
 MOD_RES 107 107 Phosphoserine.
 MOD_RES 539 539 Phosphoserine (By similarity).  
Keyword
 ATP-binding; Complete proteome; Cytoplasm; Kinase; Nucleotide-binding; Nucleus; Phosphoprotein; Reference proteome; Transferase; Ubl conjugation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 548 AA 
Protein Sequence
MAAPPASMSA APSPLQSAVA PDVPGRQAEQ NETACEDRSN AGTLDRLLPP VGTGRSPRKR 60
TTSQCKSEPP LLRTSKRTIY TAGRPPWYNE HGTQSKEAFA IGLGGGSASG KTTVARMIIE 120
ALDVPWVVLL SMDSFYKVLT QQQQEQAACN NFNFDHPDAF DFDLIISTLK KLKQGRSVQV 180
PIYDFTTHSR KKDWKTLYGA NVIIFEGIMA FADKTLLELL DMKIFVDTDS DIRLVRRLRR 240
DISERGRDIE GVIKQYNKFV KPAFDQYIQP TMRLADIVVP RGSGNTVAID LIVQHVHSQL 300
EERELSVRAA LASAHQCHPL PQTLSVLKST PQVRGMHTII RDKETSRDEF IFYSKRLMRL 360
LIEHALSFLP FQDCTVQTPQ GQDYVGKCYA GKQITGVSIL RAGETMEPAL RAVCKDVRIG 420
TILIQTNQLT GEPELHYLRL PKDISDDHVI LMDCTVSTGA AAMMAVRVLL DHDVPEDKIF 480
LLSLLMAEMG VHSVAYAFPR VRIITTAVDK RVNDLFRIIP GIGNFGDRYF GTDAVPDGSD 540
DDEAATVG 548 
Gene Ontology
 GO:0005783; C:endoplasmic reticulum; IEA:Compara.
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0016773; F:phosphotransferase activity, alcohol group as acceptor; IEA:InterPro.
 GO:0004849; F:uridine kinase activity; IEA:InterPro.
 GO:0044206; P:UMP salvage; IEA:UniProtKB-UniPathway. 
Interpro
 IPR027417; P-loop_NTPase.
 IPR006083; PRK/URK.
 IPR000764; Uridine_kinase. 
Pfam
 PF00485; PRK 
SMART
  
PROSITE
  
PRINTS
 PR00988; URIDINKINASE.