| Tag | Content |
|---|
| CPLM ID | CPLM-022718 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Gamma-butyrobetaine dioxygenase |
Protein Synonyms/Alias | Gamma-butyrobetaine hydroxylase; Gamma-BBH; Gamma-butyrobetaine,2-oxoglutarate dioxygenase |
Gene Name | Bbox1 |
Gene Synonyms/Alias | Bbh |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 72 | DDLTFDQKKVYITWP | acetylation | [1] | | 327 | LMNSKEYKYTFKMNP | acetylation | [1] |
|
Reference | [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns. Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV. Cell Rep. 2012 Aug 30;2(2):419-31. [ PMID: 22902405] |
Functional Description | Catalyzes the formation of L-carnitine from gamma- butyrobetaine. |
Sequence Annotation | METAL 38 38 Zinc (By similarity).
METAL 40 40 Zinc (By similarity).
METAL 43 43 Zinc (By similarity).
METAL 82 82 Zinc (By similarity).
METAL 202 202 Iron; catalytic (By similarity).
METAL 204 204 Iron; catalytic (By similarity).
METAL 347 347 Iron; catalytic (By similarity). |
Keyword | Carnitine biosynthesis; Complete proteome; Cytoplasm; Dioxygenase; Direct protein sequencing; Iron; Metal-binding; Oxidoreductase; Reference proteome; Zinc. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 387 AA |
Protein Sequence | MHCAILKAEA VDGARLMQIF WHDGAESLYP AVWLRDNCQC SDCYLHSAKA RKLLLEALDV 60
NIRMDDLTFD QKKVYITWPN GHYSEFEANW LKKRCFSQEA RAGLQGELFL PECQYWGSEL 120
QLPTLNFEDV LNDDDHAYKW LSSLKKVGIV RLTGAADKRG EIIKLGKRIG FLYLTFYGHT 180
WQVQDKIDAN NVAYTTGKLS FHTDYPALHH PPGVQLLHCI KQTVTGGDSE IVDGFNVCQK 240
LKEKNPQAFS ILSSTFVDFT DIGVDYCDFS VQSKHKIIEL DDKGQVVRIN FNNATRDTVF 300
DVPIERVQPF YAALKEFVDL MNSKEYKYTF KMNPGDVITF DNWRLLHGRR SYEAGTEISR 360
HLEGAYADWD VVMSRLRILR QRVMNGN 387 |
Gene Ontology | GO:0015629; C:actin cytoskeleton; IEA:Compara. GO:0005739; C:mitochondrion; IEA:Compara. GO:0008336; F:gamma-butyrobetaine dioxygenase activity; IMP:UniProtKB. GO:0005506; F:iron ion binding; IEA:InterPro. GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW. GO:0008270; F:zinc ion binding; ISS:UniProtKB. GO:0045329; P:carnitine biosynthetic process; ISS:UniProtKB. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |