UniProt Accession

 TM219_HUMAN; Q86XT9; D5FK14; Q8WVV8 

Genbank Protein ID

 FJ748884; CH471238; BC017488; BC050051 

Genbank Nucleotide ID

 ACQ72822.1; EAW79966.1; AAH17488.1; AAH50051.1 

Protein Name

 Insulin-like growth factor-binding protein 3 receptor 

Protein Synonyms/Alias

 IGFBP-3R; Transmembrane protein 219 

Gene Name

 TMEM219 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
79	RNGTVTGKWRGSHVV	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

 Cell death receptor specific for IGFBP3, may mediate caspase-8-dependent apoptosis upon ligand binding. 

Sequence Annotation

 CARBOHYD 73 73 N-linked (GlcNAc...) (Potential).
 CARBOHYD 101 101 N-linked (GlcNAc...) (Potential).
 CARBOHYD 167 167 N-linked (GlcNAc...) (Potential).  

Keyword

 Apoptosis; Cell membrane; Complete proteome; Glycoprotein; Membrane; Receptor; Reference proteome; Signal; Transmembrane; Transmembrane helix. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 240 AA 

Protein Sequence

Gene Ontology

 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
 GO:0006915; P:apoptotic process; IEA:UniProtKB-KW. 

Interpro

  

Pfam

  

SMART

  

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PRINTS