UniProt Accession

 C9JFP1_HUMAN; C9JFP1 

Genbank Protein ID

 AL590233; AL929575 

Genbank Nucleotide ID

  

Protein Name

 Semaphorin-4D 

Protein Synonyms/Alias

  

Gene Name

 SEMA4D 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
81	NALNISEKQHEVYWK	ubiquitination	[1]
104	CAEKGKSKQTECLNY	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 146 AA 

Protein Sequence

Gene Ontology

 GO:0005615; C:extracellular space; IEA:Compara.
 GO:0010693; P:negative regulation of alkaline phosphatase activity; IEA:Compara.
 GO:0045668; P:negative regulation of osteoblast differentiation; IEA:Compara.
 GO:0050732; P:negative regulation of peptidyl-tyrosine phosphorylation; IEA:Compara.
 GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Compara.
 GO:0043931; P:ossification involved in bone maturation; IEA:Compara.
 GO:0050772; P:positive regulation of axonogenesis; IEA:Compara.
 GO:0030335; P:positive regulation of cell migration; IEA:Compara.
 GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IEA:Compara.
 GO:0032321; P:positive regulation of Rho GTPase activity; IEA:Compara.
 GO:1900220; P:semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis; IEA:Compara. 

Interpro

 IPR027231; Semaphorin.
 IPR001627; Semaphorin/CD100_Ag.
 IPR015943; WD40/YVTN_repeat-like_dom. 

Pfam

 PF01403; Sema 

SMART

  

PROSITE

 PS51004; SEMA 

PRINTS