UniProt Accession

 AROK_SALTY; P63601; Q8XFE9 

Genbank Protein ID

 AE006468 

Genbank Nucleotide ID

 AAL22349.1 

Protein Name

 Shikimate kinase 1 

Protein Synonyms/Alias

 SK 1 

Gene Name

 aroK 

Gene Synonyms/Alias

 STM3487 

Created Date

 July 27, 2013 

Organism

 Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) 

NCBI Taxa ID

 99287 

Lysine Modification

Position	Peptide	Type	References
109	YLETTIEKQLARTQR	acetylation	[1]

Reference

 [1] Regulation of cellular metabolism by protein lysine acetylation.
 Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Zhou L, Zeng Y, Li H, Li Y, Shi J, An W, Hancock SM, He F, Qin L, Chin J, Yang P, Chen X, Lei Q, Xiong Y, Guan KL.
 Science. 2010 Feb 19;327(5968):1000-4. [PMID: 20167786] 

Functional Description

 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity). 

Sequence Annotation

 NP_BIND 14 19 ATP (By similarity).
 METAL 18 18 Magnesium (By similarity).
 BINDING 36 36 Substrate (By similarity).
 BINDING 60 60 Substrate (By similarity).
 BINDING 82 82 Substrate; via amide nitrogen (By
 BINDING 120 120 ATP (By similarity).
 BINDING 140 140 Substrate (By similarity).
 BINDING 157 157 ATP (By similarity).  

Keyword

 Amino-acid biosynthesis; Aromatic amino acid biosynthesis; ATP-binding; Complete proteome; Cytoplasm; Kinase; Magnesium; Metal-binding; Nucleotide-binding; Reference proteome; Transferase. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 173 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0005524; F:ATP binding; IEA:HAMAP.
 GO:0000287; F:magnesium ion binding; IEA:HAMAP.
 GO:0004765; F:shikimate kinase activity; IEA:HAMAP.
 GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:HAMAP.
 GO:0009423; P:chorismate biosynthetic process; IEA:UniProtKB-UniPathway. 

Interpro

 IPR027417; P-loop_NTPase.
 IPR000623; Shikimate_kinase/TSH1.
 IPR023000; Shikimate_kinase_CS. 

Pfam

 PF01202; SKI 

SMART

  

PROSITE

 PS01128; SHIKIMATE_KINASE 

PRINTS

 PR01100; SHIKIMTKNASE.