CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-020782
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Ankyrin repeat and EF-hand domain-containing protein 1 
Protein Synonyms/Alias
 Ankyrin repeat domain-containing protein 5 
Gene Name
 Ankef1 
Gene Synonyms/Alias
 Ankrd5 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
646IIDMIKEKLDNLPKQacetylation[1, 2]
Reference
 [1] The fasted/fed mouse metabolic acetylome: N6-acetylation differences suggest acetylation coordinates organ-specific fuel switching.
 Yang L, Vaitheesvaran B, Hartil K, Robinson AJ, Hoopmann MR, Eng JK, Kurland IJ, Bruce JE.
 J Proteome Res. 2011 Sep 2;10(9):4134-49. [PMID: 21728379]
 [2] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
 REPEAT 47 76 ANK 1.
 REPEAT 184 213 ANK 2.
 REPEAT 217 246 ANK 3.
 REPEAT 250 279 ANK 4.
 REPEAT 524 553 ANK 5.
 REPEAT 557 586 ANK 6.
 REPEAT 590 619 ANK 7.
 REPEAT 623 652 ANK 8.  
Keyword
 ANK repeat; Complete proteome; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 775 AA 
Protein Sequence
MALADKRLEN LQIYRVLQCV RNKDKKQIEK LTRLGYPELI NFTEPIDGLS ALHLASISND 60
TDMVSFLLKL GAHPDVQDHM GCTPTMRAAE LGHELSMEIL AKAKADMTIV DNEGKGVLFY 120
CILPTKRHYR CSLIALEHGA DVNNITYEGK PVFLRACEEA HDVKDMCLTF LEKGANPNAI 180
NTSTGRTALM ESSREGVLEI VRGILERGGE VNAYDNDRHH AAHFAAKGGF FDILKLLFAY 240
NGDMGLIGMD GNTPLHFAAM GGFADCCKYI AQRGCDLKWK NLEHKTPRVV AKDGGFKAAS 300
KEIRRAERTA AKLAKTGAKN PNPLWALRLH DWSIEHETSL RNAFKFVDRG DGVVSKDDFV 360
VALEERQEYA TSEQLLSVAQ MHEKSRGGGV NINEFFKGTK YLSKSYVLGS FGPKKKKRGL 420
GKKPRKGKFV LPLPICTIPE NAFPRRPDGG PPYYMIETYQ NVSDSHRFNR DHPPEHPIQD 480
DSEWYIDDPS RVFANISFIT KAGDLASLKK AIETGIPVDM KDNTYKTPLM IACASGNIDV 540
VKFLIEKGAN VNATDNFLWT PLHFACHAGQ QDIVELLVKA GASIDATSIN NSTPLSRAIE 600
SCRLDTVKYL LDMGAKFQIE NRKGHAAMDI AKAYADYRII DMIKEKLDNL PKQADNQKMK 660
GKLPKLKTEG TDVKKEEETL SSIYTVPAIT EEKKVHRDSV VYLNSLITSG FTKKVDITFI 720
PKRIWSPEAT TAELIRKREL RRERFTYEVD FEDFMMPFQK NITEKAQALE ATLKN 775 
Gene Ontology
 GO:0005509; F:calcium ion binding; IEA:InterPro. 
Interpro
 IPR002110; Ankyrin_rpt.
 IPR020683; Ankyrin_rpt-contain_dom.
 IPR011992; EF-hand-like_dom. 
Pfam
 PF12796; Ank_2 
SMART
 SM00248; ANK 
PROSITE
 PS50297; ANK_REP_REGION
 PS50088; ANK_REPEAT 
PRINTS
 PR01415; ANKYRIN.