CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-014452
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Reticulocalbin-2 
Protein Synonyms/Alias
 Calcium-binding protein ERC-55; Taipoxin-associated calcium-binding protein 49; TCBP-49 
Gene Name
 Rcn2 
Gene Synonyms/Alias
 Erc55 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
74RRLQSIIKKIDSDSDacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
 Not known. Binds calcium. 
Sequence Annotation
 DOMAIN 64 99 EF-hand 1.
 DOMAIN 100 135 EF-hand 2.
 DOMAIN 150 185 EF-hand 3.
 DOMAIN 189 224 EF-hand 4.
 DOMAIN 230 265 EF-hand 5.
 DOMAIN 266 301 EF-hand 6.
 MOTIF 317 320 Prevents secretion from ER (Potential).  
Keyword
 Calcium; Complete proteome; Direct protein sequencing; Endoplasmic reticulum; Metal-binding; Reference proteome; Repeat; Signal. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 320 AA 
Protein Sequence
MRLGPRPAVL GLLLLLLLYA AVAGASKAEE LHYPQGEHRA DYDRETLLGV QEDVDEYVKL 60
GHEEQQRRLQ SIIKKIDSDS DGFLTENELS QWIQMSFKHY AMQEAKQQFV EYDKNSDGTV 120
TWDEYNVQMY DRVIDFDENT ALDDTEEESF RQLHLKDKKR FEKANQDSGP GLNLEEFIAF 180
EHPEEVDYMT EFVIQEALEE HDKNGDGFVS LEEFLGDYRR DPTANEDPEW ILVEKDRFVN 240
DYDKDSDGRL DPQELLSWVV PNNQGIAQEE ALHLIDEMDL NSDKKLSEEE ILENQDLFLT 300
SEATDYGRQL HDDYFYHDEL 320 
Gene Ontology
 GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
 GO:0005509; F:calcium ion binding; IEA:InterPro. 
Interpro
 IPR011992; EF-hand-like_dom.
 IPR018247; EF_Hand_1_Ca_BS.
 IPR002048; EF_hand_dom. 
Pfam
 PF13202; EF_hand_3
 PF13499; EF_hand_5 
SMART
 SM00054; EFh 
PROSITE
 PS00018; EF_HAND_1
 PS50222; EF_HAND_2
 PS00014; ER_TARGET 
PRINTS