CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-043498
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Fanconi anemia group A protein 
Protein Synonyms/Alias
  
Gene Name
 FANCA 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
121AGRSLELKGQGNPVEubiquitination[1, 2, 3, 4, 5]
132NPVELITKARLFLLQubiquitination[1, 3, 4, 5]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [3] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [4] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [5] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 153 AA 
Protein Sequence
XKKLDCEREE STTDLPKAFH VCAAILECLE KRKISWLALF QLTESDLRLG RLLLRVAPDQ 60
HTRLLPFAFY SLLSYFHEDA AIREEAFLHV AVDMYLKLVQ LFVAGDTSTV SPPAGRSLEL 120
KGQGNPVELI TKARLFLLQL IPRCPKKSFS HVA 153 
Gene Ontology
  
Interpro
 IPR003516; Fanconia. 
Pfam
 PF03511; Fanconi_A 
SMART
  
PROSITE
  
PRINTS
 PR00826; FANCONIAGENE.