CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038504
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein C6 
Protein Synonyms/Alias
  
Gene Name
 C6 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
428TKNKLSEKYGGSFLQubiquitination[1]
439SFLQGSEKSISLVQGubiquitination[1]
486NPAVVDYKLAPITDLubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Disulfide bond; EGF-like domain; Reference proteome; Sushi. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 931 AA 
Protein Sequence
MTRHLTLCFI LLVMLIDKSE ACFCDHYPWT HWSSCSKSCN SGTQSRQRQV VVNDYYWKNL 60
CDKLCIKQET RECNLQTCPI NCVLGDYGTW SDCDPCTEKQ VKVKSVLRPS QFGGQPCTEP 120
LVTFQPCVPS KLCKIEETNC KNKFLCDSGR CIPSKLECNG ENDCGDNSDE RNCGRTKPVC 180
TRIYTPIPSV QLMGTGFHFL AGEPRGEVLD NSFTGGICKL VKTSRASNPY RVSANLENVN 240
FEVQTIEDDL KTEFYKNLIS FEKNKNEDSL SVDERTKFFP IPIFHFSEKN EHSHYSSAFN 300
KVIKASHKKD SSFIRIHKLI KVLNFTMKAT DLQLSDVFLK ALVHLPLEYN SAVYSRIFDD 360
FGTHYFTSGS LGGKYDLIYQ FSRQELQNSG LTEEEAQNCV QYETKKLKFL YMEIHKEDTC 420
TKNKLSEKYG GSFLQGSEKS ISLVQGGRSQ QAAALAWEKG TSGPEENVYS EWLESVKENP 480
AVVDYKLAPI TDLVRNIPCA VTKRNNLRRA LQEYAAKFDP CQCAPCPNNG RPRLSGTECL 540
CVCQSGTYGE NCERRSPGYK SDAVDGNWGC WSSWSACNAA YRRSRTRECN NPAPQRGGQS 600
CGGKDQQEED CTVSIMENVG QPCINDDEEM KEVDLAEPEA ESGCSQPPLP ENAFTWNEKK 660
LYSVGEEVEI SCLTGFTAVG FQYLRCLPDR TWSQGDVECQ RTSCLKPVVQ DVLTISPFQR 720
VYQIGESIEL TCPRGFVVAG PSRYTCKEDS WTPPISNSLT CEQGEQIFAW TCHLHVLSAL 780
RPNTCFPSSD SAYSEDLCIF DGGSSQYFTS SACKFLAGKC LNNTQSHFVH SGSCQEGLQL 840
EWGLERLKLA VNSTKRVSCG YNTCYDWENC SAHTSNCVCL LPPQCSKDEN QLYCVKIGSS 900
MREKTVNICT LGAVRCANIK VEILNPGRCP D 931 
Gene Ontology
 GO:0005579; C:membrane attack complex; IEA:InterPro.
 GO:0006955; P:immune response; IEA:InterPro.
 GO:0001701; P:in utero embryonic development; IGI:MGI. 
Interpro
 IPR013032; EGF-like_CS.
 IPR002350; Kazal_dom.
 IPR023415; LDLR_class-A_CS.
 IPR002172; LDrepeatLR_classA_rpt.
 IPR001862; MAC_perforin.
 IPR020864; MACPF.
 IPR020863; MACPF_CS.
 IPR000436; Sushi_SCR_CCP.
 IPR000884; Thrombospondin_1_rpt. 
Pfam
 PF00057; Ldl_recept_a
 PF01823; MACPF
 PF00084; Sushi
 PF00090; TSP_1 
SMART
 SM00032; CCP
 SM00192; LDLa
 SM00457; MACPF
 SM00209; TSP1 
PROSITE
 PS00022; EGF_1
 PS51465; KAZAL_2
 PS01209; LDLRA_1
 PS50068; LDLRA_2
 PS00279; MACPF_1
 PS51412; MACPF_2
 PS50923; SUSHI
 PS50092; TSP1 
PRINTS
 PR00764; COMPLEMENTC9.