CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025406
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 SWI/SNF complex subunit SMARCC2 
Protein Synonyms/Alias
  
Gene Name
 Smarcc2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
33NVRLWLGKNYKKYIQubiquitination[1]
101LAAAYKFKSDQGWRRacetylation[2]
565TKAGRKGKELDDLVPacetylation[3]
599FPEKGKEKPADMQNFubiquitination[1]
725RVASAAAKSALEEFSubiquitination[1]
735LEEFSKMKEEVPTALubiquitination[1]
856IVDPEKDKEPTEGQEubiquitination[1]
903ALAAAAVKAKHLAAVubiquitination[1]
905AAAAVKAKHLAAVEEubiquitination[1]
971AFHMEQLKYAEMRARubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [3] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Nucleus; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1130 AA 
Protein Sequence
MAVRKKDGGP NVKYYEAADT VTQFDNVRLW LGKNYKKYIQ AEPPTNKSLS SLVVQLLQFQ 60
EEVFGKHVSN APLTKLPIKC FLDFKAGGSL CHILAAAYKF KSDQGWRRYD FQNPSRMDRN 120
VEMFMTIEKS LVQNNCLSRP NIFLCPEIEP KLLGKLKDIV KRHQGTISED KSNASHVVYP 180
VPGNLEEEEW VRPVMKRDKQ VLLHWGYYPD SYDTWIPASE IEASVEDAPT PEKPRKVHAK 240
WILDTDTFNE WMNEEDYEVS DDKSPVSRRK KISAKTLTDE VNSPDSDRRD KKGGNYKKRK 300
RSPSPSPTPE AKKKNAKKGP STPYTKSKRG HREEEQEDLT KDMDEPSPVP NVEEVTLPKT 360
VNTKKDSESA PVKGGTMTDL DEQDDESMET TGKDEDENST GNKGEQTKNP DLHEDNVTEQ 420
THHIIIPSYA AWFDYNSVHA IERRALPEFF NGKNKSKTPE IYLAYRNFMI DTYRLNPQEY 480
LTSTACRRNL AGDVCAIMRV HAFLEQWGLI NYQVDAESRP TPMGPPPTSH FHVLADTPSG 540
LVPLQPKPPQ GRQVDADTKA GRKGKELDDL VPETAKGKPE LQSSASQQML NFPEKGKEKP 600
ADMQNFGLRT DMYTKKNVPS KSKAAASATR EWTEQETLLL LEALEMYKDD WNKVSEHVGS 660
RTQDECILHF LRLPIEDPYL EDSEASLGPL AYQPIPFSQS GNPVMSTVAF LASVVDPRVA 720
SAAAKSALEE FSKMKEEVPT ALVEAHVRKV EEAAKVTGKA DPAFGLESSG IAGTASDEPE 780
RIEESGTEEA RPEGQAADEK KEPKEPREGG GAVEEEAKEE ISEVPKKDEE KGKEGDSEKE 840
SEKSDGDPIV DPEKDKEPTE GQEEVLKEVA EPEGERKTKV ERDIGEGNLS TAAAAALAAA 900
AVKAKHLAAV EERKIKSLVA LLVETQMKKL EIKLRHFEEL ETIMDREREA LEYQRQQLLA 960
DRQAFHMEQL KYAEMRARQQ HFQQMHQQQQ QQPPTLPPGS QPIPPTGAAG PPTVHGLAVP 1020
PAAVASAPPG SGAPPGSLGP SEQIGQAGTT AGPQQPQQAG APQPGAVPPG VPPPGPHGPS 1080
PFPNQPTPPS MMPGAVPGSG HPGVADPGTP LPPDPTAPSP GTVTPVPPPQ 1130 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-KW.
 GO:0003682; F:chromatin binding; IEA:InterPro.
 GO:0003677; F:DNA binding; IEA:InterPro. 
Interpro
 IPR001357; BRCT_dom.
 IPR000953; Chromo_domain/shadow.
 IPR009057; Homeodomain-like.
 IPR001005; SANT/Myb.
 IPR017884; SANT_dom.
 IPR007526; SWIRM.
 IPR011991; WHTH_DNA-bd_dom. 
Pfam
 PF00249; Myb_DNA-binding
 PF04433; SWIRM 
SMART
 SM00298; CHROMO
 SM00717; SANT 
PROSITE
 PS51293; SANT
 PS50934; SWIRM 
PRINTS