UniProt Accession

 Q91YH6_MOUSE; Q91YH6 

Genbank Protein ID

 AC090647; BC017127; AF435091; AK052604; AK052707; AK078810; AK168980; CH466523 

Genbank Nucleotide ID

 AAH17127.1; AAN45856.1; BAC35059.1; BAC35108.1; BAC37404.1; BAE40781.1; EDK99099.1 

Protein Name

 ATPase, H+ transporting, lysosomal V1 subunit B1 

Protein Synonyms/Alias

 ATPase, H+ transporting, lysosomal V1 subunit B1, isoform CRA_a; Protein Atp6v1b1; Vacuolar proton translocating ATPase B1 isoform 

Gene Name

 Atp6v1b1 

Gene Synonyms/Alias

 mCG_142376 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
131	RIFNGSGKPIDKGPA	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Hydrogen ion transport; Ion transport; Reference proteome; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 513 AA 

Protein Sequence

Gene Ontology

 GO:0016324; C:apical plasma membrane; IDA:UniProtKB.
 GO:0016323; C:basolateral plasma membrane; IDA:UniProtKB.
 GO:0005829; C:cytosol; IDA:UniProtKB.
 GO:0016328; C:lateral plasma membrane; IDA:UniProtKB.
 GO:0005902; C:microvillus; IDA:UniProtKB.
 GO:0033180; C:proton-transporting V-type ATPase, V1 domain; IEA:InterPro.
 GO:0016471; C:vacuolar proton-transporting V-type ATPase complex; ISS:UniProtKB.
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0015078; F:hydrogen ion transmembrane transporter activity; IMP:UniProtKB.
 GO:0016820; F:hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances; IEA:InterPro.
 GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
 GO:0046034; P:ATP metabolic process; IEA:InterPro.
 GO:0055074; P:calcium ion homeostasis; ISS:UniProtKB.
 GO:0007588; P:excretion; ISS:UniProtKB.
 GO:0001503; P:ossification; ISS:UniProtKB.
 GO:0045851; P:pH reduction; ISS:UniProtKB.
 GO:0007605; P:sensory perception of sound; ISO:MGI. 

Interpro

 IPR020003; ATPase_a/bsu_AS.
 IPR004100; ATPase_a/bsu_N.
 IPR000793; ATPase_F1/V1/A1-cplx_a/bsu_C.
 IPR000194; ATPase_F1/V1/A1_a/bsu_nucl-bd.
 IPR005723; ATPase_V1-cplx_bsu.
 IPR027417; P-loop_NTPase.
 IPR022879; V-ATPase_su_B/beta. 

Pfam

 PF00006; ATP-synt_ab
 PF00306; ATP-synt_ab_C
 PF02874; ATP-synt_ab_N 

SMART

  

PROSITE

 PS00152; ATPASE_ALPHA_BETA 

PRINTS