CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-029620
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 D-tyrosyl-tRNA(Tyr) deacylase 
Protein Synonyms/Alias
  
Gene Name
 Dtd1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
48ELEHMVRKILNLRVFacetylation[1]
61VFEDESGKHWSKSVMacetylation[1]
115SFLEQLRKSYRPELIacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405
Functional Description
 Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity). 
Sequence Annotation
  
Keyword
 Complete proteome; Hydrolase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 209 AA 
Protein Sequence
MKAVVQRVTR ASVTVGGEQI SAIGRGICVL LGISMEDTQK ELEHMVRKIL NLRVFEDESG 60
KHWSKSVMDK EYEVLCVSQF TLQCVLKGNK PDLHLAMPTE QAESFYNSFL EQLRKSYRPE 120
LIRDGKFGAY MQVHIQNDGP VTIELESPAP GAASSDPKQL SKLEKQQQRK EKTRAKGPSE 180
SSKERNTPRK EDRSASSGAE GDVSSEREP 209 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0005730; C:nucleolus; IEA:Compara.
 GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
 GO:0019478; P:D-amino acid catabolic process; IEA:InterPro. 
Interpro
 IPR023509; DTD-like_dom.
 IPR003732; DTyrtRNA_deacyls. 
Pfam
 PF02580; Tyr_Deacylase 
SMART
  
PROSITE
  
PRINTS