CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-022721
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Integrin beta-1-binding protein 2 
Protein Synonyms/Alias
 Melusin 
Gene Name
 Itgb1bp2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
213VGRHDWAKQLPASCRubiquitination[1]
313HPDSLAEKARAGVLLubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 May play a role during maturation and/or organization of muscles cells. 
Sequence Annotation
 DOMAIN 5 64 CHORD 1.
 DOMAIN 150 209 CHORD 2.
 DOMAIN 216 305 CS.
 MOTIF 28 31 SH3-binding (Potential).
 MOTIF 70 79 SH3-binding (Potential).
 MOTIF 159 162 SH2-binding (Potential).
 MOTIF 173 176 SH3-binding (Potential).
 MOTIF 235 238 SH2-binding (Potential).
 METAL 5 5 Zinc 1 (By similarity).
 METAL 10 10 Zinc 1 (By similarity).
 METAL 24 24 Zinc 1 (By similarity).
 METAL 27 27 Zinc 2 (By similarity).
 METAL 42 42 Zinc 2 (By similarity).
 METAL 43 43 Zinc 2 (By similarity).
 METAL 59 59 Zinc 2 (By similarity).
 METAL 64 64 Zinc 1 (By similarity).
 METAL 150 150 Zinc 3 (By similarity).
 METAL 155 155 Zinc 3 (By similarity).
 METAL 169 169 Zinc 3 (By similarity).
 METAL 172 172 Zinc 4 (By similarity).
 METAL 187 187 Zinc 4 (By similarity).
 METAL 188 188 Zinc 4 (By similarity).
 METAL 204 204 Zinc 4 (By similarity).
 METAL 209 209 Zinc 3 (By similarity).  
Keyword
 Complete proteome; Metal-binding; Reference proteome; Repeat; SH3-binding; Zinc. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 350 AA 
Protein Sequence
MSLLCYNKGC GQHFDPNTNL PDSCRYHPGV PIFHDALKGW SCCRKRTVDF SEFLNIKGCT 60
VGLHCAEKLP EVPPQPEGPA TSSLQEQKPL NTIPKSAETL FRERPKSEMP PKLLPLLISQ 120
ALGVALEQKE LDQEPGAGLD NSLIWTGSSC QNPGCDAVYQ GPESDATPCT YHPGAPRFHE 180
GMKSWSCCGI QTLDFGAFLA QPGCRVGRHD WAKQLPASCR HDWHQTDSVV VLTVYGQIPL 240
PAFNWVKASQ TELHVHIVFD GNRVFQAQMK LWGVINVEQS SVSLMPSRVE ISLVKADPGS 300
WAQLEHPDSL AEKARAGVLL EMDEEESEDS DDDLSWTEEE DEEEEEAMGE 350 
Gene Ontology
 GO:0030018; C:Z disc; IDA:MGI.
 GO:0005509; F:calcium ion binding; IDA:MGI.
 GO:0008270; F:zinc ion binding; IDA:MGI. 
Interpro
 IPR007051; CHORD.
 IPR007052; CS-like_domain.
 IPR017447; CS_domain.
 IPR008978; HSP20-like_chaperone. 
Pfam
 PF04968; CHORD
 PF04969; CS 
SMART
  
PROSITE
 PS51401; CHORD
 PS51203; CS 
PRINTS