CPLM 1.0 - Compendium of Protein Lysine Modification
Tag
Content
CPLM ID
CPLM-027621
UniProt Accession
Q8TCW4_HUMAN
;
Q8TCW4
Genbank Protein ID
AY091460
Genbank Nucleotide ID
AAM12030.1
Protein Name
DNA-directed RNA polymerase
Protein Synonyms/Alias
Gene Name
Gene Synonyms/Alias
Created Date
July 27, 2013
Organism
Homo sapiens (Human)
NCBI Taxa ID
9606
Lysine Modification
Position
Peptide
Type
References
42
ANINFLR
K
LVQNGPE
ubiquitination
[1]
347
TPGQGLL
K
AKYELLN
ubiquitination
[1]
Reference
[1] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
Chen Z, Zhou Y, Song J, Zhang Z.
Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [
PMID: 23603789
]
Functional Description
Sequence Annotation
Keyword
DNA-directed RNA polymerase; Nucleotidyltransferase; Transcription; Transferase.
Sequence Source
UniProt (SWISSPROT/TrEMBL); GenBank; EMBL
Protein Length
387 AA
Protein Sequence
GRTVISPDPN LRIDEVAVPV HVAKILTFPE KVNKANINFL RKLVQNGPEV HPGANFIQQR 60
HTQMKRFLKY GNREKMAQEL KYGDIVERHL IDGDVVLFNR QPSLHKLSIM AHLARVKPHR 120
TFRFNECVCT PYNADFDGDE MNLHLPQTEE AKAEALVLMG TKANLVTPRN GEPLIAAIQD 180
FLTGAYLLTL KDTFFDRAKA CQIIASILVG KDEKIKVRLP PPTILKPVTL WTGKQIFSVI 240
LRPSDDNPVR ANLRTKGKQY CGKGEDLCAN DSYVTIQNSE LMSGSMDKGT LGSGSKNNIF 300
YILLRDWGQN EAADAMSRLA RLAPVYLSNR GFSIGIGDVT PGQGLLKAKY ELLNAGYKKC 360
DEYIEALNTG KLQQQPGCTA EETLEAL 387
Gene Ontology
GO:0005634
; C:nucleus; IEA:InterPro.
GO:0003682
; F:chromatin binding; IEA:Compara.
GO:0003677
; F:DNA binding; IEA:InterPro.
GO:0003899
; F:DNA-directed RNA polymerase activity; IEA:UniProtKB-KW.
GO:0032549
; F:ribonucleoside binding; IEA:InterPro.
GO:0008270
; F:zinc ion binding; IEA:InterPro.
GO:0006351
; P:transcription, DNA-dependent; IEA:InterPro.
Interpro
IPR009010
; Asp_de-COase-like_dom.
IPR000722
; RNA_pol_asu.
IPR015700
; RNA_pol_III_lsu.
IPR006592
; RNA_pol_N.
IPR007066
; RNA_pol_Rpb1_3.
Pfam
PF00623
; RNA_pol_Rpb1_2
PF04983
; RNA_pol_Rpb1_3
SMART
SM00663
; RPOLA_N
PROSITE
PRINTS