CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-003865
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Phosphoenolpyruvate carboxykinase [ATP] 
Protein Synonyms/Alias
  
Gene Name
 PCK1 
Gene Synonyms/Alias
 PEPC; PPC1; YKR097W 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
19STSEVEQKIRQELALacetylation[1]
514NWSQGESKYRGAVTNacetylation[1]
Reference
 [1] Protein acetylation microarray reveals that NuA4 controls key metabolic target regulating gluconeogenesis.
 Lin YY, Lu JY, Zhang J, Walter W, Dang W, Wan J, Tao SC, Qian J, Zhao Y, Boeke JD, Berger SL, Zhu H.
 Cell. 2009 Mar 20;136(6):1073-84. [PMID: 19303850] 
Functional Description
  
Sequence Annotation
 NP_BIND 250 257 ATP (Potential).  
Keyword
 ATP-binding; Complete proteome; Decarboxylase; Direct protein sequencing; Gluconeogenesis; Lyase; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 549 AA 
Protein Sequence
MSPSKMNATV GSTSEVEQKI RQELALSDEV TTIRRNAPAA VLYEDGLKEN KTVISSSGAL 60
IAYSGVKTGR SPKDKRIVEE PTSKDEIWWG PVNKPCSERT WSINRERAAD YLRTRDHIYI 120
VDAFAGWDPK YRIKVRVVCA RAYHALFMTN MLIRPTEEEL AHFGEPDFTV WNAGQFPANL 180
HTQDMSSKST IEINFKAMEM IILGTEYAGE MKKGIFTVMF YLMPVHHNVL TLHSSANQGI 240
QNGDVTLFFG LSGTGKTTLS ADPHRLLIGD DEHCWSDHGV FNIEGGCYAK CINLSAEKEP 300
EIFDAIKFGS VLENVIYDEK SHVVDYDDSS ITENTRCAYP IDYIPSAKIP CLADSHPKNI 360
ILLTCDASGV LPPVSKLTPE QVMYHFISGY TSKMAGTEQG VTEPEPTFSS CFGQPFLALH 420
PIRYATMLAT KMSQHKANAY LINTGWTGSS YVSGGKRCPL KYTRAILDSI HDGSLANETY 480
ETLPIFNLQV PTKVNGVPAE LLNPAKNWSQ GESKYRGAVT NLANLFVQNF KIYQDRATPD 540
VLAAGPQFE 549 
Gene Ontology
 GO:0005829; C:cytosol; IDA:SGD.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0004612; F:phosphoenolpyruvate carboxykinase (ATP) activity; IDA:SGD.
 GO:0006094; P:gluconeogenesis; IEP:SGD. 
Interpro
 IPR001272; PEP_carboxykinase_ATP.
 IPR013035; PEP_carboxykinase_C.
 IPR008210; PEP_carboxykinase_N.
 IPR015994; PEPCK_ATP_CS. 
Pfam
 PF01293; PEPCK_ATP 
SMART
  
PROSITE
 PS00532; PEPCK_ATP 
PRINTS