UniProt Accession

 MT1DP_HUMAN; A1L3X4; Q86YX1 

Genbank Protein ID

 AF348999 

Genbank Nucleotide ID

 AAO32959.2 

Protein Name

 Putative metallothionein MT1DP 

Protein Synonyms/Alias

  

Gene Name

 MT1DP 

Gene Synonyms/Alias

 MTM 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
30	EYKCTSCKKNCCSCC	ubiquitination	[1]
43	CCPMGCAKCAQGCT*	ubiquitination	[2]

Reference

 [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 

Functional Description

 Metallothioneins have a high content of cysteine residues that bind various heavy metals (By similarity). 

Sequence Annotation

 REGION 1 29 Beta.
 REGION 30 49 Alpha.
 METAL 5 5 Divalent metal cation; cluster B (By
 METAL 7 7 Divalent metal cation; cluster B (By
 METAL 13 13 Divalent metal cation; cluster B (By
 METAL 15 15 Divalent metal cation; cluster B (By
 METAL 19 19 Divalent metal cation; cluster B (By
 METAL 21 21 Divalent metal cation; cluster B (By
 METAL 26 26 Divalent metal cation; cluster B (By
 METAL 29 29 Divalent metal cation; cluster B (By
 METAL 33 33 Divalent metal cation; cluster A (By
 METAL 34 34 Divalent metal cation; cluster A (By
 METAL 36 36 Divalent metal cation; cluster A (By
 METAL 37 37 Divalent metal cation; cluster A (By
 METAL 41 41 Divalent metal cation; cluster A (By
 METAL 44 44 Divalent metal cation; cluster A (By
 METAL 48 48 Divalent metal cation; cluster A (By  

Keyword

 Complete proteome; Metal-binding; Metal-thiolate cluster; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 49 AA 

Protein Sequence

Gene Ontology

 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. 

Interpro

 IPR017854; Metalthion_dom.
 IPR023587; Metalthion_dom_vert.
 IPR003019; Metalthion_sfam_euk.
 IPR000006; Metalthion_vert. 

Pfam

 PF00131; Metallothio 

SMART

  

PROSITE

  

PRINTS

 PR00860; MTVERTEBRATE.