UniProt Accession

 SRSF9_MOUSE; Q9D0B0; Q9CRN3 

Genbank Protein ID

 AK011621; AK020084; BC012217 

Genbank Nucleotide ID

 BAB27740.1; BAB31986.1; AAH12217.1 

Protein Name

 Serine/arginine-rich splicing factor 9 

Protein Synonyms/Alias

 Splicing factor, arginine/serine-rich 9 

Gene Name

 Srsf9 

Gene Synonyms/Alias

 Sfrs9 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
37	DLEDLFYKYGRIREI	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 Plays a role in constitutive splicing and can modulate the selection of alternative splice sites. Represses the splicing of MAPT/Tau exon 10 (By similarity). 

Sequence Annotation

 DOMAIN 15 90 RRM 1.
 DOMAIN 112 188 RRM 2.
 REGION 189 201 Interacts with SAFB1 (By similarity).
 MOD_RES 190 190 Phosphoserine (By similarity).
 MOD_RES 193 193 Phosphotyrosine (By similarity).
 MOD_RES 194 194 Phosphoserine (By similarity).
 MOD_RES 196 196 Phosphoserine (By similarity).
 MOD_RES 205 205 Phosphoserine.
 MOD_RES 209 209 Phosphoserine (By similarity).
 MOD_RES 212 212 Phosphoserine.
 MOD_RES 217 217 Phosphoserine.  

Keyword

 3D-structure; Complete proteome; mRNA processing; mRNA splicing; Nucleus; Phosphoprotein; Reference proteome; Repeat; Repressor; RNA-binding. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 222 AA 

Protein Sequence

Gene Ontology

 GO:0005730; C:nucleolus; IEA:Compara.
 GO:0000166; F:nucleotide binding; IEA:InterPro.
 GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
 GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
 GO:0048025; P:negative regulation of mRNA splicing, via spliceosome; ISS:UniProtKB.
 GO:0008380; P:RNA splicing; IEA:UniProtKB-KW. 

Interpro

 IPR012677; Nucleotide-bd_a/b_plait.
 IPR000504; RRM_dom. 

Pfam

 PF00076; RRM_1 

SMART

 SM00360; RRM 

PROSITE

 PS50102; RRM 

PRINTS