CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-020374
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 YTH domain family protein 1 
Protein Synonyms/Alias
 Dermatomyositis associated with cancer putative autoantigen 1; DACA-1 
Gene Name
 YTHDF1 
Gene Synonyms/Alias
 C20orf21 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
191EQGMVGLKIGDVSSSubiquitination[1]
370ESHPVLEKLKAAHSYubiquitination[1]
372HPVLEKLKAAHSYNPubiquitination[1]
419CSTEHGNKRLDSAFRubiquitination[1]
500RLENNDNKPVTNSRDubiquitination[1]
541DDFAHYEKRQEEEEVubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
 DOMAIN 389 523 YTH.
 MOD_RES 2 2 N-acetylserine.  
Keyword
 Acetylation; Alternative splicing; Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 559 AA 
Protein Sequence
MSATSVDTQR TKGQDNKVQN GSLHQKDTVH DNDFEPYLTG QSNQSNSYPS MSDPYLSSYY 60
PPSIGFPYSL NEAPWSTAGD PPIPYLTTYG QLSNGDHHFM HDAVFGQPGG LGNNIYQHRF 120
NFFPENPAFS AWGTSGSQGQ QTQSSAYGSS YTYPPSSLGG TVVDGQPGFH SDTLSKAPGM 180
NSLEQGMVGL KIGDVSSSAV KTVGSVVSSV ALTGVLSGNG GTNVNMPVSK PTSWAAIASK 240
PAKPQPKMKT KSGPVMGGGL PPPPIKHNMD IGTWDNKGPV PKAPVPQQAP SPQAAPQPQQ 300
VAQPLPAQPP ALAQPQYQSP QQPPQTRWVA PRNRNAAFGQ SGGAGSDSNS PGNVQPNSAP 360
SVESHPVLEK LKAAHSYNPK EFEWNLKSGR VFIIKSYSED DIHRSIKYSI WCSTEHGNKR 420
LDSAFRCMSS KGPVYLLFSV NGSGHFCGVA EMKSPVDYGT SAGVWSQDKW KGKFDVQWIF 480
VKDVPNNQLR HIRLENNDNK PVTNSRDTQE VPLEKAKQVL KIISSYKHTT SIFDDFAHYE 540
KRQEEEEVVR KERQSRNKQ 559 
Gene Ontology
  
Interpro
 IPR007275; YTH_domain. 
Pfam
 PF04146; YTH 
SMART
  
PROSITE
 PS50882; YTH 
PRINTS