CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-032750
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Histone acetyltransferase GCN5, putative 
Protein Synonyms/Alias
  
Gene Name
 TGVEG_057910 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Toxoplasma gondii 
NCBI Taxa ID
 5811 
Lysine Modification
Position
Peptide
Type
References
1046RTGALGSKKGPFGRAacetylation[1]
1047TGALGSKKGPFGRAGacetylation[1]
1057FGRAGFAKGEKGLRAacetylation[1, 2]
1060AGFAKGEKGLRAASLacetylation[1, 2]
1080ALLSTLEKHSSSWPFacetylation[1, 2]
Reference
 [1] Protein intrinsic disorder in the acetylome of intracellular and extracellular Toxoplasma gondii.
 Xue B, Jeffers V, Sullivan WJ, Uversky VN.
 Mol Biosyst. 2013 Apr 5;9(4):645-57. [PMID: 23403842]
 [2] Lysine acetylation is widespread on proteins of diverse function and localization in the protozoan parasite Toxoplasma gondii.
 Jeffers V, Sullivan WJ Jr.
 Eukaryot Cell. 2012 Jun;11(6):735-42. [PMID: 22544907] 
Functional Description
  
Sequence Annotation
  
Keyword
 Acyltransferase; Bromodomain; Complete proteome; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1169 AA 
Protein Sequence
METVEVPAFL EAANSAEAPR PASPAREVDV QLTVPCPRDG ADAGEAVGTR KRSRGPADRA 60
EEASGRTHSA AEEPRAKEGG LSPASRDGDS GQSRKRVKRE WASGGRLEQR GPLGVAAHAV 120
EWRRASAEAR GDARQTPDAA RGSSSRVDRF AGEDGVLDEG DLFSPSPFWP FFSACDPVAL 180
APAPTVCPDT PSVSVVSACS RLLRAPPRDL ASEATLDSLA GNVHVEESLW RGCESPNILE 240
ILRDILVVFA KDPSTQLSKM FHTASLLAPY QAASCHAASD AERDKKGDEA DSARRRDHHE 300
KERDHGGRPL AVGESADSEG RHPGATEHAA GEAAGEAADG VRTADGDACQ ERRAEGAGAA 360
NGVAPLGMPE PAHAVGDRER ENGSLEVKKA EREDAERLEN GGGGQTAGED RDDVNDDPPD 420
TEREPGPQQA GRRCLEANGV RGVKQEQENA GTDEERVLYL QLKEVVLSVA AALEIQQLEP 480
PRKRKDPKKK PHSSSASSAC RRGRGNAVSS SVSCFSASAN CTSEDGERSG GDAAGARANG 540
EIKAASDETY SDRRVPGGLH EESEKNEAAR EKTREESGQT RTPASESGSN AFVGFAQQSE 600
SRANSGVSSR PAEERGNEET FPDKEEEGAP AQREKHVAWA ETTGAETARN SDESEARRDP 660
RLETCPLCDC QEDDAAWTRH GILPYDILYE KWKAFLMKGA PTGLGLASFF GKSFIFHTLH 720
AALPALLEEL ANTVVGTELR RFVLALAAAV GLSSSHAEEL LHRAVAVRSS RLESILPSET 780
GLGFLHRDAG GAREEELGII SFCCVTNDRQ PLHMRHLVTV KNIFSRQLPK MPREYIVRLV 840
FDRAHFTFCL CKQGRVIGGV CFRPYFREKF AEIAFLAVTS TEQVKGYGTR LMNHLKEHVK 900
KSGIEYFLTY ADNFAVGYFR KQGFSSKITM PRDRWLGYIK DYDGGTLMEC RLSTRINYLK 960
LSQLLALQKL AVKRRIEQSA PSVVCPSLSF WKENPGQLLM PSAIPGLAEL NKNGELSLLL 1020
SSGRVGAAPQ GSGALPGGRT GALGSKKGPF GRAGFAKGEK GLRAASLKAQ IAALLSTLEK 1080
HSSSWPFRRP VSVSEAPDYY EVVRRPIDIS TMKKRNRNGD YRTKEAFQED LLLMFDNCRV 1140
YNSPDTIYYK YADELQAFIW PKVEALGSF 1169 
Gene Ontology
 GO:0004402; F:histone acetyltransferase activity; IEA:EC.
 GO:0016573; P:histone acetylation; IEA:GOC. 
Interpro
 IPR016181; Acyl_CoA_acyltransferase.
 IPR001487; Bromodomain.
 IPR018359; Bromodomain_CS.
 IPR000182; GNAT_dom. 
Pfam
 PF13508; Acetyltransf_7
 PF00439; Bromodomain 
SMART
 SM00297; BROMO 
PROSITE
 PS00633; BROMODOMAIN_1
 PS50014; BROMODOMAIN_2
 PS51186; GNAT 
PRINTS
 PR00503; BROMODOMAIN.