CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-029553
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 DNA replication licensing factor MCM6 
Protein Synonyms/Alias
 Mcm6 protein; Minichromosome maintenance complex component 6; Minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae), isoform CRA_a 
Gene Name
 Mcm6 
Gene Synonyms/Alias
 rCG_45934 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
197RFLLDTNKSRFVDFQacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; DNA replication; DNA-binding; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 821 AA 
Protein Sequence
MDLAAAAEPG AGSQHPEVRD EVAEKCQKLF LDFLEEFQGS DGEIKYLQFA EELIRPERNT 60
LVVSFADLEQ FNQQLSTTIQ EEFYRVYPYL CRALKTFVKD RKEIPFAKDF YVAFQDLPTR 120
HKIRELTSSR IGLLTRISGQ VVRTHPVHPE LVSGTFLCLD CQTVIKDVEQ QFKYTQPSIC 180
RNPVCANRKR FLLDTNKSRF VDFQKVRIQE TQAELPRGSI PRSLEVVLRA EAVESAQAGD 240
RCDFTGTLIV VPDVSKLSTP GARAETNSRV SGADGYETEG IRGLRALGVR DLSYRLVFLA 300
CYVAPTNPRF GGKELRDEEQ TAESIKNQMT VKEWEKVFEM SQDKNLYHNL CTSLFPTIHG 360
NDEVKRGVLL MLFGGVPKTT GEGTSLRGDI NVCIVGDPST AKSQFLKHVD EFSPRAVYTS 420
GKASSAAGLT AAVVRDEESH EFVIEAGALM LADNGVCCID EFDKMDMRDQ VAIHEAMEQQ 480
TISITKAGVK ATLNARTSIL AAANPVSGHY DRSKSLKQNI NLSAPIMSRF DLFFILVDEC 540
NEVTDYAIAR RIVDLHSRIE ESIDRVYSLD DIRRYLLFAR QFKPKISKES EDFIVEQYKR 600
LRQRDGSGIT KSSWRITVRQ LESMIRLSES MARMHCCDEV QPKHVKEAFR LLNKSIIRVE 660
TPDVNLDQEE EIQMETDEGP GGINGHADSP APVNGFNGSG EDASQETVPK PSLRLGFAEY 720
CRISNLIVLH LRKMEEEEDE SALKRSELVN WYLKEIESEI DSEEELINKK RIIEKVVHRL 780
THYDHVLIEL TQAGLKGSSE GSESYEEDPY LVVNPNYLLE D 821 
Gene Ontology
 GO:0042555; C:MCM complex; IEA:Compara.
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0004003; F:ATP-dependent DNA helicase activity; IEA:Compara.
 GO:0003697; F:single-stranded DNA binding; IEA:Compara.
 GO:0006270; P:DNA replication initiation; IEA:InterPro.
 GO:0006268; P:DNA unwinding involved in replication; IEA:Compara. 
Interpro
 IPR008049; MCM6.
 IPR018525; MCM_CS.
 IPR001208; MCM_DNA-dep_ATPase.
 IPR012340; NA-bd_OB-fold.
 IPR027417; P-loop_NTPase.
 IPR004039; Rubredoxin-type_fold. 
Pfam
 PF00493; MCM 
SMART
 SM00350; MCM 
PROSITE
 PS00847; MCM_1
 PS50051; MCM_2 
PRINTS
 PR01657; MCMFAMILY.
 PR01662; MCMPROTEIN6.