CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-001339
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 ADP-ribosylation factor GTPase-activating protein AGD10 
Protein Synonyms/Alias
 ARF GAP AGD10; Protein ARF-GAP DOMAIN 10; AtAGD10; Protein MATERNAL EFFECT EMBRYO ARREST 28; Protein ROOT AND POLLEN ARFGAP 
Gene Name
 AGD10 
Gene Synonyms/Alias
 MEE28; RPA; At2g35210; T4C15.12 
Created Date
 July 27, 2013 
Organism
 Arabidopsis thaliana (Mouse-ear cress) 
NCBI Taxa ID
 3702 
Lysine Modification
Position
Peptide
Type
References
383KNMAEETKKKLGSVAacetylation[1]
Reference
 [1] Lysine acetylation is a widespread protein modification for diverse proteins in Arabidopsis.
 Wu X, Oh MH, Schwarz EM, Larue CT, Sivaguru M, Imai BS, Yau PM, Ort DR, Huber SC.
 Plant Physiol. 2011 Apr;155(4):1769-78. [PMID: 21311030
Functional Description
 GTPase-activating protein (GAP) for ADP ribosylation factor (ARF). Activates ARF1 and ARF2. Required for female gametophyte development. Involved in root hair and pollen tube growth. 
Sequence Annotation
 DOMAIN 10 128 Arf-GAP.
 ZN_FING 25 48 C4-type.  
Keyword
 Alternative splicing; Coiled coil; Complete proteome; Golgi apparatus; GTPase activation; Metal-binding; Reference proteome; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 395 AA 
Protein Sequence
MASENLNDKI SVFKKLKAKS DNKICFDCNA KNPTWASVTY GIFLCIDCSA VHRSLGVHIS 60
FVRSTNLDSW SSEQLKMMIY GGNNRAQVFF KQYGWSDGGK TEAKYTSRAA DLYKQILAKE 120
VAKSKAEEEL DLPPSPPDST QVPNGLSSIK TSEALKESNT LKQQEKPDVV PVSPRISRSV 180
KKPLGAKKTG KTGGLGARKL TTKSSGTLYD QKPEESVIIQ ATSPVSAKSA RSSFSSRFDY 240
ADNVQNREDY MSPQVVSHVA PPKSSGFFEE ELEMNGGRFQ KKPITSSSKL QIQETDEARK 300
KFTNAKSISS AQYFGNDNNS ADLEAKSSLK KFSGSSAISS ADLFGDGDGD FPLDLTAGDL 360
LNRLSLQAQQ DISSLKNMAE ETKKKLGSVA SSLWV 395 
Gene Ontology
 GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
 GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0009793; P:embryo development ending in seed dormancy; IMP:TAIR.
 GO:0009555; P:pollen development; IMP:TAIR.
 GO:0043547; P:positive regulation of GTPase activity; IEA:GOC.
 GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. 
Interpro
 IPR001164; ArfGAP. 
Pfam
 PF01412; ArfGap 
SMART
 SM00105; ArfGap 
PROSITE
 PS50115; ARFGAP 
PRINTS
 PR00405; REVINTRACTNG.